Literature DB >> 32063768

Use of 68Ga DOTATATE, a new molecular imaging agent, for neuroendocrine tumors.

Raymond Andrew LeBlanc1, Umesh D Oza1, Ryan Hayden1, Hanna Fanous1.   

Abstract

Neuroendocrine tumors (NET), such as insulinomas and carcinoid tumors, can be challenging to diagnose since patients often present with vague symptoms. Adding to the challenge, these tumors are often occult on typical cross-sectional imaging modalities. Because of these challenges, there has been an increase in the utilization of radiopharmaceuticals that take advantage of specific receptors expressed by NET. Among the multiple radiopharmaceuticals that can be used, 68Ga DOTATATE is emerging as the most sensitive and specific imaging agent. We present a case where 68Ga DOTATATE was used to diagnose a well-differentiated neuroendocrine tumor.
Copyright © 2020 Baylor University Medical Center.

Entities:  

Keywords:  68Ga DOTATATE; Carcinoid; F-18 fludeoxyglucose; neuroendocrine tumors; positron emission tomography/computed tomography

Year:  2019        PMID: 32063768      PMCID: PMC6988632          DOI: 10.1080/08998280.2019.1678338

Source DB:  PubMed          Journal:  Proc (Bayl Univ Med Cent)        ISSN: 0899-8280


  5 in total

1.  Evaluation of neuroendocrine liver metastases: a comparison of dynamic contrast-enhanced magnetic resonance imaging and positron emission tomography/computed tomography.

Authors:  Marco Armbruster; Steven Sourbron; Alexander Haug; Christoph J Zech; Michael Ingrisch; Christoph J Auernhammer; Konstantin Nikolaou; Philipp M Paprottka; Carsten Rist; Maximilian F Reiser; Wieland H Sommer
Journal:  Invest Radiol       Date:  2014-01       Impact factor: 6.016

2.  Functional imaging of neuroendocrine tumors with combined PET/CT using 68Ga-DOTATATE (DOTA-DPhe1,Tyr3-octreotate) and 18F-FDG.

Authors:  Irfan Kayani; Jamshed B Bomanji; Ashley Groves; Gerard Conway; Sveto Gacinovic; Thida Win; John Dickson; Martyn Caplin; Peter Joseph Ell
Journal:  Cancer       Date:  2008-06       Impact factor: 6.860

3.  68Ga-DOTATATE PET in neuroectodermal tumours: first experience.

Authors:  Zarni Win; Adil Al-Nahhas; David Towey; Jeannie F Todd; Domenico Rubello; Val Lewington; Philip Gishen
Journal:  Nucl Med Commun       Date:  2007-05       Impact factor: 1.690

Review 4.  Nothing But NET: A Review of Neuroendocrine Tumors and Carcinomas.

Authors:  Bryan Oronsky; Patrick C Ma; Daniel Morgensztern; Corey A Carter
Journal:  Neoplasia       Date:  2017-11-05       Impact factor: 5.715

5.  (68)Ga-DOTATATE positron emission tomography/computed tomography scan in the detection of bone metastases in pediatric neuroendocrine tumors.

Authors:  Reema Goel; Jaya Shukla; Deepak Bansal; Kushaljit Sodhi; Anish Bhattacharya; Ram Kumar Marwaha; Bhagwant Rai Mittal
Journal:  Indian J Nucl Med       Date:  2014-01
  5 in total

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