Mototsugu Tanaka1, Yoshitaka Ishibashi2, Yoshifumi Hamasaki1, Yuka Kamijo2, Mayumi Idei3, Takuya Kawahara4, Takahiro Nishi5, Michio Takeda6, Hiroshi Nonaka7,8, Masaomi Nangaku1, Naobumi Mise9. 1. Division of Nephrology and Endocrinology, The University of Tokyo School of Medicine, Japan. 2. Division of Nephrology, Department of Medicine, Japanese Red Cross Medical Center, Tokyo, Japan. 3. Department of Clinical Laboratory Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan. 4. Clinical Research Support Center, The University of Tokyo Hospital, Japan. 5. Nishi Clinic, Tokyo, Japan. 6. Akihabara Izumi Clinic, Tokyo, Japan. 7. Nonaka Clinic, Tokyo, Japan. 8. Deceased. 9. Division of Nephrology, Department of Medicine, Mitsui Memorial Hospital, Tokyo, Japan.
Abstract
BACKGROUND: The health-related quality of life (HRQOL) of dialysis patients has not been well examined, especially in combination therapy with peritoneal dialysis and hemodialysis (PD+HD) patients. We compared the HRQOL of PD+HD patients with that of HD and PD patients. METHODS: A multicenter, cross-sectional study was conducted on 36 PD+HD, 103 HD, and 90 PD patients in Japan who completed the Kidney Disease Quality of Life Short Form 36, version 1.3. HRQOL scores were summarized into physical- (PCS), mental- (MCS), role/social- (RCS), and kidney disease component summaries (KDCS). RESULTS: Of the PD+HD patients, 31 (86%) transferred from PD and 5 (14%) transferred from HD. They had the longest dialysis vintage and the smallest urine volume. PCS, MCS, and KDCS HRQOL scores of PD+HD patients were comparable with those of HD and PD patients. However, the RCS score for PD+HD was significantly higher than that for HD (p = 0.020) and comparable with that for PD. PD+HD and PD were associated with significantly higher RCS scores than HD after adjusting for age, gender, diabetic nephropathy, dialysis vintage, ischemic heart disease, and peripheral arterial disease. CONCLUSIONS: For RCS, HRQOL in PD+HD patients was better than that in HD and comparable with that in PD patients, whereas the PCS, MCS, and KDCS HRQOL scores of PD+HD patients were comparable with those of HD and PD patients.
BACKGROUND: The health-related quality of life (HRQOL) of dialysis patients has not been well examined, especially in combination therapy with peritoneal dialysis and hemodialysis (PD+HD) patients. We compared the HRQOL of PD+HDpatients with that of HD and PDpatients. METHODS: A multicenter, cross-sectional study was conducted on 36 PD+HD, 103 HD, and 90 PDpatients in Japan who completed the Kidney Disease Quality of Life Short Form 36, version 1.3. HRQOL scores were summarized into physical- (PCS), mental- (MCS), role/social- (RCS), and kidney disease component summaries (KDCS). RESULTS: Of the PD+HDpatients, 31 (86%) transferred from PD and 5 (14%) transferred from HD. They had the longest dialysis vintage and the smallest urine volume. PCS, MCS, and KDCS HRQOL scores of PD+HDpatients were comparable with those of HD and PDpatients. However, the RCS score for PD+HD was significantly higher than that for HD (p = 0.020) and comparable with that for PD. PD+HD and PD were associated with significantly higher RCS scores than HD after adjusting for age, gender, diabetic nephropathy, dialysis vintage, ischemic heart disease, and peripheral arterial disease. CONCLUSIONS: For RCS, HRQOL in PD+HDpatients was better than that in HD and comparable with that in PDpatients, whereas the PCS, MCS, and KDCS HRQOL scores of PD+HDpatients were comparable with those of HD and PDpatients.
Entities:
Keywords:
KDQOL; PD+HD; SF-36r; end-stage renal disease; residual renal function