Hamza E Ahmed Mohamed1,2, Shakeeb Afridi3, Ali T Khalil1,2,4, Muhammad Ali3, Tanzeel Zohra5, Ribqa Akhtar5, Aamer Ikram5, Zabta K Shinwari3,6,7, Malik Maaza1,2. 1. UNESCO UNISA Africa Chair in Nanosciences & Nanotechnology, College of Graduate Studies, University of South Africa, Muckleneuk Ridge, PO Box 392, Pretoria, Gauteng, South Africa. 2. Nanosciences African Network (NANOAFNET), iThemba LABS-National Research Foundation, 1 Old Faure Road, Somerset West 7129, PO Box 722, Somerset West, Western Cape, South Africa. 3. Department of Biotechnology, Quaid-i-Azam University, Islamabad, 45320, Pakistan. 4. Department of Biotechnology, Qarshi University, Lahore, 53720, Pakistan. 5. National Institute of Health, Islamabad, 44000, Pakistan. 6. Pakistan Academy of Sciences, Islamabad, 44000, Pakistan. 7. National Council for Tibb, Islamabad, 44000, Pakistan.
Abstract
Aim: To demonstrate synthesis of cerium oxide nanoparticles (CeO2 NPs) by a green method using Hyphaene thebaica, and investigate their therapeutic applications. Materials & methods: Structural, vibrational and luminescent properties were established using x-ray diffraction, Fourier transformed infrared spectroscopy, Raman spectroscopy, ultraviolet absorption spectroscopy, selected area electron diffraction, electron microscopy and photolumincence spectroscopy. Therapeutic properties were established using different in vitro assays. Results: CeO2 NPs were determined to be crystalline in nature with a grain size of approximately 14 nm. They had characteristic Ce-O vibration at 481 cm-1. Photoluminescence spectra revealed broad bands at 463 and 600 nm. ζ potential was recorded as -17.2 mV. Potent antimicrobial and antiviral properties with hemocompatibility were reported. Conclusion: Biosynthesized CeO2 NPs revealed multifunctional therapeutic properties.
Aim: To demonstrate synthesis of cerium oxide nanoparticles (CeO2 NPs) by a green method using Hyphaene thebaica, and investigate their therapeutic applications. Materials & methods: Structural, vibrational and luminescent properties were established using x-ray diffraction, Fourier transformed infrared spectroscopy, Raman spectroscopy, ultraviolet absorption spectroscopy, selected area electron diffraction, electron microscopy and photolumincence spectroscopy. Therapeutic properties were established using different in vitro assays. Results:CeO2 NPs were determined to be crystalline in nature with a grain size of approximately 14 nm. They had characteristic Ce-O vibration at 481 cm-1. Photoluminescence spectra revealed broad bands at 463 and 600 nm. ζ potential was recorded as -17.2 mV. Potent antimicrobial and antiviral properties with hemocompatibility were reported. Conclusion: Biosynthesized CeO2 NPs revealed multifunctional therapeutic properties.
Authors: Adrián García-Salvador; Alberto Katsumiti; Elena Rojas; Carol Aristimuño; Mónica Betanzos; Marta Martínez-Moro; Sergio E Moya; Felipe Goñi-de-Cerio Journal: Nanomaterials (Basel) Date: 2021-06-16 Impact factor: 5.076
Authors: Alexander B Shcherbakov; Vladimir V Reukov; Alexander V Yakimansky; Elena L Krasnopeeva; Olga S Ivanova; Anton L Popov; Vladimir K Ivanov Journal: Polymers (Basel) Date: 2021-03-17 Impact factor: 4.329