Shen Han1, Chuan-Yu Wei2, Zong-Liu Hou2, Ya-Xiong Li1, Yun-Chuan Ding3, Xue-Feng Guang4, Dong Huang5, Zhu-Hui Na1, Wen-Min Chen1, Li-Hong Jian G6. 1. Department of Cardiovascular Surgery and Key Laboratory of Cardiovascular Disease of Yunnan Province, Kunming, Yunnan, China. 2. Department of Central Laboratory, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China. 3. Department of Ultrasound, Yan'an Affiliated Hospital of Kunming Medical University and Key Laboratory of Cardiovascular Disease of Yunnan Province, Kunming, Yunnan, China. 4. Department of Cardiology, Yan'an Affiliated Hospital of Kunming Medical University and Key Laboratory of Cardiovascular Disease of Yunnan Province, Kunming, Yunnan, China. 5. Department of Cardiovascular Surgery, Yan'an Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China. 6. First People's Hospital of Yunnan Province; Kunming, Yunnan, China.
Abstract
OBJECTIVE: To investigate the prevalence and risk factors of congenital heart disease in Yunnan, China which has diverse ethnic groups. METHODS: This cross-sectional study enrolled 244,023 children from 2010 to 2015. To diagnose CHD, a conventional physical examination was used to screen suspicious cases, which were further confirmed by echocardiography. RESULTS: A total of 1695 children were diagnosed with CHD. The estimated prevalence was 6.94%. Atrial septal defects were the most common cardiac abnormalities. A higher prevalence of CHD was observed with preterm birth, low birth weight, maternal age ≥35 years, and high-altitude regions. The prevalence also showed differences between diverse ethnic groups. CONCLUSIONS: The prevalence of CHD in China may have ethnic differences.
OBJECTIVE: To investigate the prevalence and risk factors of congenital heart disease in Yunnan, China which has diverse ethnic groups. METHODS: This cross-sectional study enrolled 244,023 children from 2010 to 2015. To diagnose CHD, a conventional physical examination was used to screen suspicious cases, which were further confirmed by echocardiography. RESULTS: A total of 1695 children were diagnosed with CHD. The estimated prevalence was 6.94%. Atrial septal defects were the most common cardiac abnormalities. A higher prevalence of CHD was observed with preterm birth, low birth weight, maternal age ≥35 years, and high-altitude regions. The prevalence also showed differences between diverse ethnic groups. CONCLUSIONS: The prevalence of CHD in China may have ethnic differences.