| Literature DB >> 32060111 |
Pradeep Kumar Mada1, Daniel Alexander Saldaña Koppel2, Majd Al Shaarani3, Andrew Stevenson Joel Chandranesan4.
Abstract
Primary cutaneous aspergillosis (PCA) occurs through inoculation of fungal spores directly into the skin from the environment through disrupted skin such as in burns, surgery or penetrating trauma patients. Most cases reported in literature were in the immunocompromised, rarely in immunocompetent patients. The characteristic lesion of cutaneous aspergillosis is a black eschar on a red plaque, or nodule at the site of skin injury. The diagnosis of PCA can be made by identifying hyphal forms on routine H&E staining or special stains such as periodic acid-Schiff or Gomori methenamine-silver stains on skin biopsy and by fungal cultures. We report a case of an 80-year-old farmer who developed cutaneous aspergillosis after a surgical procedure without any systemic spread. The diagnosis was made by histopathology and tissue fungal cultures. He was treated with incision and drainage followed by oral voriconazole for 4 weeks; which led to clinical recovery. © BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.Entities:
Keywords: dermatological; drugs: infectious diseases; exposures; pathology; skin
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Year: 2020 PMID: 32060111 PMCID: PMC7046428 DOI: 10.1136/bcr-2019-233020
Source DB: PubMed Journal: BMJ Case Rep ISSN: 1757-790X