Literature DB >> 32060102

Translating Basic Science Discoveries into Improved Outcomes for Glioblastoma.

Peter B Dirks1, Mark R Gilbert2, Eric C Holland3, Elizabeth A Maher4, William A Weiss5.   

Abstract

Members of the scientific and clinical neuro-oncology community met in April 2019 to discuss the current challenges and opportunities associated with translating basic science discoveries in glioblastoma for improved survival of patients. A summary of key points of these discussions is presented in this article. ©2020 American Association for Cancer Research.

Entities:  

Year:  2020        PMID: 32060102      PMCID: PMC7269826          DOI: 10.1158/1078-0432.CCR-19-3924

Source DB:  PubMed          Journal:  Clin Cancer Res        ISSN: 1078-0432            Impact factor:   12.531


  12 in total

1.  Rapid Conversion of Mutant IDH1 from Driver to Passenger in a Model of Human Gliomagenesis.

Authors:  Tor-Christian Aase Johannessen; Joydeep Mukherjee; Pavithra Viswanath; Shigeo Ohba; Sabrina M Ronen; Rolf Bjerkvig; Russell O Pieper
Journal:  Mol Cancer Res       Date:  2016-07-18       Impact factor: 5.852

2.  Analysis and visualization of linked molecular and clinical cancer data by using Oncoscape.

Authors:  Lisa G McFerrin; Michael Zager; Jianan Zhang; Gretchen Krenn; Robert McDermott; Desert Horse-Grant; Emily Silgard; Kara Colevas; Paul Shannon; Hamid Bolouri; Eric C Holland
Journal:  Nat Genet       Date:  2018-09       Impact factor: 38.330

Review 3.  Single-Cell RNA Sequencing in Cancer: Lessons Learned and Emerging Challenges.

Authors:  Mario L Suvà; Itay Tirosh
Journal:  Mol Cell       Date:  2019-07-11       Impact factor: 17.970

4.  Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma.

Authors:  Brett E Johnson; Tali Mazor; Chibo Hong; Michael Barnes; Koki Aihara; Cory Y McLean; Shaun D Fouse; Shogo Yamamoto; Hiroki Ueda; Kenji Tatsuno; Saurabh Asthana; Llewellyn E Jalbert; Sarah J Nelson; Andrew W Bollen; W Clay Gustafson; Elise Charron; William A Weiss; Ivan V Smirnov; Jun S Song; Adam B Olshen; Soonmee Cha; Yongjun Zhao; Richard A Moore; Andrew J Mungall; Steven J M Jones; Martin Hirst; Marco A Marra; Nobuhito Saito; Hiroyuki Aburatani; Akitake Mukasa; Mitchel S Berger; Susan M Chang; Barry S Taylor; Joseph F Costello
Journal:  Science       Date:  2013-12-12       Impact factor: 47.728

5.  DNA Methylation and Somatic Mutations Converge on the Cell Cycle and Define Similar Evolutionary Histories in Brain Tumors.

Authors:  Tali Mazor; Aleksandr Pankov; Brett E Johnson; Chibo Hong; Emily G Hamilton; Robert J A Bell; Ivan V Smirnov; Gerald F Reis; Joanna J Phillips; Michael J Barnes; Ahmed Idbaih; Agusti Alentorn; Jenneke J Kloezeman; Martine L M Lamfers; Andrew W Bollen; Barry S Taylor; Annette M Molinaro; Adam B Olshen; Susan M Chang; Jun S Song; Joseph F Costello
Journal:  Cancer Cell       Date:  2015-09-14       Impact factor: 31.743

6.  Evolutionary Trajectories of IDHWT Glioblastomas Reveal a Common Path of Early Tumorigenesis Instigated Years ahead of Initial Diagnosis.

Authors:  Verena Körber; Jing Yang; Pankaj Barah; Yonghe Wu; Damian Stichel; Zuguang Gu; Michael Nai Chung Fletcher; David Jones; Bettina Hentschel; Katrin Lamszus; Jörg Christian Tonn; Gabriele Schackert; Michael Sabel; Jörg Felsberg; Angela Zacher; Kerstin Kaulich; Daniel Hübschmann; Christel Herold-Mende; Andreas von Deimling; Michael Weller; Bernhard Radlwimmer; Matthias Schlesner; Guido Reifenberger; Thomas Höfer; Peter Lichter
Journal:  Cancer Cell       Date:  2019-03-21       Impact factor: 31.743

Review 7.  Functional diversity of astrocytes in neural circuit regulation.

Authors:  Lucile Ben Haim; David H Rowitch
Journal:  Nat Rev Neurosci       Date:  2016-12-01       Impact factor: 34.870

8.  Multidimensional scaling of diffuse gliomas: application to the 2016 World Health Organization classification system with prognostically relevant molecular subtype discovery.

Authors:  Patrick J Cimino; Michael Zager; Lisa McFerrin; Hans-Georg Wirsching; Hamid Bolouri; Bettina Hentschel; Andreas von Deimling; David Jones; Guido Reifenberger; Michael Weller; Eric C Holland
Journal:  Acta Neuropathol Commun       Date:  2017-05-22       Impact factor: 7.801

9.  Tracking tumour evolution in glioma through liquid biopsies of cerebrospinal fluid.

Authors:  Alexandra M Miller; Ronak H Shah; Elena I Pentsova; Maryam Pourmaleki; Samuel Briggs; Natalie Distefano; Youyun Zheng; Anna Skakodub; Smrutiben A Mehta; Carl Campos; Wan-Ying Hsieh; S Duygu Selcuklu; Lilan Ling; Fanli Meng; Xiaohong Jing; Aliaksandra Samoila; Tejus A Bale; Dana W Y Tsui; Christian Grommes; Agnes Viale; Mark M Souweidane; Viviane Tabar; Cameron W Brennan; Anne S Reiner; Marc Rosenblum; Katherine S Panageas; Lisa M DeAngelis; Robert J Young; Michael F Berger; Ingo K Mellinghoff
Journal:  Nature       Date:  2019-01-23       Impact factor: 49.962

10.  Childhood cerebellar tumours mirror conserved fetal transcriptional programs.

Authors:  Maria C Vladoiu; Ibrahim El-Hamamy; Laura K Donovan; Nada Jabado; Lincoln Stein; Michael D Taylor; Hamza Farooq; Borja L Holgado; Yogi Sundaravadanam; Vijay Ramaswamy; Liam D Hendrikse; Sachin Kumar; Stephen C Mack; John J Y Lee; Vernon Fong; Kyle Juraschka; David Przelicki; Antony Michealraj; Patryk Skowron; Betty Luu; Hiromichi Suzuki; A Sorana Morrissy; Florence M G Cavalli; Livia Garzia; Craig Daniels; Xiaochong Wu; Maleeha A Qazi; Sheila K Singh; Jennifer A Chan; Marco A Marra; David Malkin; Peter Dirks; Lawrence Heisler; Trevor Pugh; Karen Ng; Faiyaz Notta; Eric M Thompson; Claudia L Kleinman; Alexandra L Joyner
Journal:  Nature       Date:  2019-05-01       Impact factor: 49.962

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  4 in total

1.  IFN-γ induces PD-L1 through p38/JNK/ERK signaling pathways and counteracts the tumor promoting effect mediated by PD-L1 in Glioblastoma.

Authors:  Huafang Jia; Xiaoli Xie; Long Wang; Lijuan Wang; Fengyuan Che
Journal:  Comput Intell Neurosci       Date:  2022-06-29

2.  Utility of Human-Derived Models for Glioblastoma.

Authors:  Xujun Luo; William A Weiss
Journal:  Cancer Discov       Date:  2020-07       Impact factor: 38.272

3.  Tumor edge-to-core transition promotes malignancy in primary-to-recurrent glioblastoma progression in a PLAGL1/CD109-mediated mechanism.

Authors:  Chaoxi Li; Hee Jin Cho; Daisuke Yamashita; Moaaz Abdelrashid; Qin Chen; Soniya Bastola; Gustavo Chagoya; Galal A Elsayed; Svetlana Komarova; Saya Ozaki; Yoshihiro Ohtsuka; Takeharu Kunieda; Harley I Kornblum; Toru Kondo; Do-Hyun Nam; Ichiro Nakano
Journal:  Neurooncol Adv       Date:  2020-11-27

4.  Genomic profiling of newly diagnosed glioblastoma patients and its potential for clinical utility - a prospective, translational study.

Authors:  Dorte S Nørøxe; Christina W Yde; Olga Østrup; Signe R Michaelsen; Ane Y Schmidt; Savvas Kinalis; Mathias H Torp; Jane Skjøth-Rasmussen; Jannick Brennum; Petra Hamerlik; Hans S Poulsen; Finn C Nielsen; Ulrik Lassen
Journal:  Mol Oncol       Date:  2020-09-18       Impact factor: 7.449

  4 in total

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