Literature DB >> 32056070

Persisting autoimmune heparin-induced thrombocytopenia after elective abdominal aortic aneurysm repair: a case report.

Guillaume Roberge1,2, Tobias Tritschler3,4, Caleb MacGillivray5, Laurence Dufresne6, Sudhir Kumar Nagpal6, Dimitrios Scarvelis3.   

Abstract

Persisting heparin-induced thrombocytopenia (HIT) is characterized by ongoing thrombocytopenia more than 7 days after stopping heparin. It is part of cases referred to as autoimmune HIT (aHIT). In contrast to typical HIT cases, aHIT involves heparin-independent platelet activation mechanism highlighted by a strongly positive functional assay done without heparin. We report the first case of persisting HIT after an elective abdominal aortic aneurysm repair presenting with arterial and venous thrombosis, and describe the potential role of intravenous immunoglobulin in such patients.

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Keywords:  Case report; Heparin; Immunoglobulin; Thrombocytopenia; Thrombosis

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Year:  2020        PMID: 32056070     DOI: 10.1007/s11239-020-02062-2

Source DB:  PubMed          Journal:  J Thromb Thrombolysis        ISSN: 0929-5305            Impact factor:   2.300


  1 in total

1.  Acute lower limb ischemia caused by vaccine-induced immune thrombotic thrombocytopenia: focus on perioperative considerations for 2 cases.

Authors:  Guillaume Roberge; Benoit Côté; Anthony Calabrino; Nathalie Gilbert; Nathalie Gagnon
Journal:  Thromb J       Date:  2022-07-04
  1 in total

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