| Literature DB >> 32056070 |
Guillaume Roberge1,2, Tobias Tritschler3,4, Caleb MacGillivray5, Laurence Dufresne6, Sudhir Kumar Nagpal6, Dimitrios Scarvelis3.
Abstract
Persisting heparin-induced thrombocytopenia (HIT) is characterized by ongoing thrombocytopenia more than 7 days after stopping heparin. It is part of cases referred to as autoimmune HIT (aHIT). In contrast to typical HIT cases, aHIT involves heparin-independent platelet activation mechanism highlighted by a strongly positive functional assay done without heparin. We report the first case of persisting HIT after an elective abdominal aortic aneurysm repair presenting with arterial and venous thrombosis, and describe the potential role of intravenous immunoglobulin in such patients.Entities:
Keywords: Case report; Heparin; Immunoglobulin; Thrombocytopenia; Thrombosis
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Year: 2020 PMID: 32056070 DOI: 10.1007/s11239-020-02062-2
Source DB: PubMed Journal: J Thromb Thrombolysis ISSN: 0929-5305 Impact factor: 2.300