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Literature DB >> 32055490

Therapeutic strategies for uncommon testis cancer histologies: teratoma with malignant transformation and malignant testicular sex cord stromal tumors.

Mounsif Azizi¹, Ahmet M Aydin¹, Salim K Cheriyan¹, Charles C Peyton¹, Matthew Montanarella¹, Scott M Gilbert^1,2, Wade J Sexton¹.

Abstract

Testicular cancer is the most common solid malignancy in male adolescents and young adults, with germ cell derived seminomas and non-seminomas being by far the most common histologies. Teratoma with somatic-type malignancy is a rare chemo-resistant phenotype of testis cancer associated with poor prognosis in patients with advanced stage disease. Malignant gonadal-stromal tumors comprise 5% of testicular neoplasms and approximately 10% are malignant and considered chemo-radiation resistant. Prognostic factors and treatment strategies for these uncommon histologies are lacking. 2020 Translational Andrology and Urology. All rights reserved.

Entities: Disease Species

Keywords: Germ cell neoplasms; malignant transformation; sex cord-gonadal stromal tumors; teratoma

Year: 2020 PMID： 32055490 PMCID： PMC6995843 DOI： 10.21037/tau.2019.09.08

Source DB: PubMed Journal: Transl Androl Urol ISSN： 2223-4683

79 in total

1. A nationwide cohort study of stage I seminoma patients followed on a surveillance program.

Authors: Mette Saksø Mortensen; Jakob Lauritsen; Maria Gry Gundgaard; Mads Agerbæk; Niels Vilstrup Holm; Ib Jarle Christensen; Hans von der Maase; Gedske Daugaard
Journal: Eur Urol Date: 2014-07-23 Impact factor: 20.096

2. Spermatocytic seminoma of testis with sarcomatous transformation. A report of five cases.

Authors: L D True; C N Otis; W Delprado; R E Scully; J Rosai
Journal: Am J Surg Pathol Date: 1988-02 Impact factor: 6.394

Review 3. Testicular sertoli cell tumours and relative sub-types. Analysis of clinical and prognostic features.

Authors: Matteo Giglio; Mauro Medica; Aldo Franco De Rose; Francesco Germinale; Jean Louis Ravetti; Giorgio Carmignani
Journal: Urol Int Date: 2003 Impact factor: 2.089

Review 4. Large cell calcifying Sertoli cell tumor of the testis: contrasting features of six malignant and six benign tumors and a review of the literature.

Authors: S S Kratzer; T M Ulbright; A Talerman; J R Srigley; L M Roth; G R Wahle; M Moussa; J K Stephens; A Millos; R H Young
Journal: Am J Surg Pathol Date: 1997-11 Impact factor: 6.394

5. Does retroperitoneal lymph node dissection have a curative role for patients with sex cord-stromal testicular tumors?

Authors: Ashraf A Mosharafa; Richard S Foster; Richard Bihrle; Michael O Koch; Thomas M Ulbright; Lawrence H Einhorn; John P Donohue
Journal: Cancer Date: 2003-08-15 Impact factor: 6.860

6. Testicular and paratesticular tumors and tumor-like lesions of ovarian common epithelial and müllerian types. A report of four cases and review of the literature.

Authors: R H Young; R E Scully
Journal: Am J Clin Pathol Date: 1986-08 Impact factor: 2.493

7. Clinical outcomes of local and metastatic testicular sex cord-stromal tumors.

Authors: Jonathan L Silberstein; Wassim M Bazzi; Emily Vertosick; Brett S Carver; George J Bosl; Darren R Feldman; Dean F Bajorin; Robert J Motzer; Hikmat Al-Ahmadie; Victor E Reuter; Joel Sheinfeld
Journal: J Urol Date: 2014-02-08 Impact factor: 7.450

Therapeutic strategies for uncommon testis cancer histologies: teratoma with malignant transformation and malignant testicular sex cord stromal tumors.

1. A nationwide cohort study of stage I seminoma patients followed on a surveillance program.

2. Spermatocytic seminoma of testis with sarcomatous transformation. A report of five cases.

Review 3. Testicular sertoli cell tumours and relative sub-types. Analysis of clinical and prognostic features.

Review 4. Large cell calcifying Sertoli cell tumor of the testis: contrasting features of six malignant and six benign tumors and a review of the literature.

5. Does retroperitoneal lymph node dissection have a curative role for patients with sex cord-stromal testicular tumors?

6. Testicular and paratesticular tumors and tumor-like lesions of ovarian common epithelial and müllerian types. A report of four cases and review of the literature.

7. Clinical outcomes of local and metastatic testicular sex cord-stromal tumors.

8. Leydig cell tumors of the testis. A clinicopathological analysis of 40 cases and review of the literature.

9. Accuracy of frozen section examination of testicular tumors of uncertain origin.

10. Chemotherapy for teratoma with malignant transformation.

1. LAPTM5 Plays a Key Role in the Diagnosis and Prognosis of Testicular Germ Cell Tumors.

2. Bilateral testicular adrenal rest tumors in a patient with nonclassical congenital adrenal hyperplasia.