Literature DB >> 32055146

Challenges in successful management of haemophilic knee arthropathy: Our experience in a tertiary centre.

Mohan Thadi1, Prajwal P Mane1,2, Anubhav Sharma1.   

Abstract

BACKGROUND: Haemophilia is characterized by a partial or complete deficiency of clotting factor VIII or IX. The repeated bleeding episodes into the joints contributes to subsequent chronic arthropathy which debilitates the patient and affects the quality of life. There are lot of hurdles in successful management of such patients. We present our experience in dealing such patients.
MATERIALS AND METHODS: 24 patients (27 knees) with haemophilic knee arthropathy were included. The preoperative VAS (Visual Analogue Scale) and KSS (Knee Society Score) were assessed. All underwent total knee arthroplasty with stemmed constrained prosthesis. Postoperatively VAS and KSS were analysed at the end of 12 months.
RESULTS: The mean preoperative VAS was 8.2 (Range: 7-10), mean KSS clinical score was 39.9 (Range: 12-61) and mean KSS functional score was 51.4(Range: 20-70). The mean postoperative VAS was 2.7(Range: 2-4), mean KSS clinical score was 70.5 (Range: 61-80) and mean KSS functional score was 74.2(Range: 60-80). There was statistical significant difference between preoperative and post-operative scores. At the end of 12 months, 17 patients (63%) had good outcome, seven patients (26%) had fair and three patients (11%) had excellent outcome as per the KSS scores.
CONCLUSIONS: Total knee arthroplasty has good outcome with respect to clinical as well as functional outcome in haemophilic arthropathy. Although the results and outcome of total knee arthroplasty in haemophilic knee arthropathy may still be inferior to the results seen in a normal individual, a multidisciplinary approach yields a better functional and quality of living in such haemophilic patients.
© 2019 Professor P K Surendran Memorial Education Foundation. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Arthropathy; Constrained prosthesis; Haemophilia; Knee deformity; Total knee arthroplasty

Year:  2019        PMID: 32055146      PMCID: PMC7005516          DOI: 10.1016/j.jor.2019.11.011

Source DB:  PubMed          Journal:  J Orthop        ISSN: 0972-978X


  12 in total

1.  Preoperative knee stiffness and total knee arthroplasty outcomes.

Authors:  Mitch Winemaker; Wael A Rahman; Danielle Petruccelli; Justin de Beer
Journal:  J Arthroplasty       Date:  2012-01-27       Impact factor: 4.757

2.  Comparison of total knee arthroplasty in stiff knees and knees with good preoperative range of motion.

Authors:  Dharmesh Khatri; Rajesh Malhotra; Surya Bhan; Vijay Kumar; Krishna Kiran Eachempati
Journal:  J Knee Surg       Date:  2009-10       Impact factor: 2.757

3.  Total knee arthroplasty in patients with stiff knees.

Authors:  Chi-Hsiang Hsu; Po-Chun Lin; Wun-Schen Chen; Jun-Wen Wang
Journal:  J Arthroplasty       Date:  2011-06-30       Impact factor: 4.757

4.  Long-term results of primary total knee replacement in patients with hemophilia.

Authors:  Mauricio Silva; James V Luck
Journal:  J Bone Joint Surg Am       Date:  2005-01       Impact factor: 5.284

5.  Total knee replacement in haemophilic arthropathy.

Authors:  E C Rodriguez-Merchan
Journal:  J Bone Joint Surg Br       Date:  2007-02

Review 6.  Total joint arthroplasty: the final solution for knee and hip when synovitis could not be controlled.

Authors:  E C Rodriguez-Merchan
Journal:  Haemophilia       Date:  2007-11       Impact factor: 4.287

Review 7.  Co-morbidity in the ageing haemophilia patient: the down side of increased life expectancy.

Authors:  E P Mauser-Bunschoten; D E Fransen Van De Putte; R E G Schutgens
Journal:  Haemophilia       Date:  2009-02-18       Impact factor: 4.287

8.  Total knee arthroplasty in hemophilic arthropathy.

Authors:  Dhiren S Sheth; Donna Oldfield; Catherine Ambrose; Terry Clyburn
Journal:  J Arthroplasty       Date:  2004-01       Impact factor: 4.757

9.  Total knee arthroplasty in hemophilic arthropathy.

Authors:  Isabelle Legroux-Gérot; Guillaume Strouk; Armelle Parquet; Jenny Goodemand; François Gougeon; Bernard Duquesnoy
Journal:  Joint Bone Spine       Date:  2003-02       Impact factor: 4.929

Review 10.  Modern management of haemophilic arthropathy.

Authors:  Leslie Raffini; Catherine Manno
Journal:  Br J Haematol       Date:  2007-03       Impact factor: 6.998

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