Literature DB >> 32051790

Nutritional Supplements for Age-Related Macular Degeneration.

Ninel Z Gregori1, Raquel Goldhardt2.   

Abstract

The Age-Related Eye Disease Study (AREDS) and The Age-Related Eye Disease Study 2 (AREDS2), are the only large-scale, long-term, randomized controlled trials to demonstrate a role of nutritional supplements in reducing risk of progression to advanced forms of age-related macular degeneration (AMD). This review summarizes the study design, main results, and implications of these trials in the clinical care of nonexudative AMD patients. In addition, it discusses other recent prospective studies focusing on efficacy of nutritional supplementation for prevention or slowing progression of AMD as well as briefly discusses possible effect of genotypes on response to AREDS supplementation.

Entities:  

Keywords:  Age-Related Eye Disease Study; Nutritional supplements; age-related macular degeneration; vitamins

Year:  2015        PMID： 32051790      PMCID： PMC7015456          DOI： 10.1007/s40135-014-0059-z

Source DB:  PubMed          Journal:  Curr Ophthalmol Rep        ISSN： 2167-4868


  27 in total

Review 1.  Molecular pathology of age-related macular degeneration.

Authors:  Xiaoyan Ding; Mrinali Patel; Chi-Chao Chan
Journal:  Prog Retin Eye Res       Date:  2008-11-06       Impact factor: 21.198

2.  Visual outcome after antioxidant supplementation.

Authors:  Stephen Beatty; John M Nolan; Katherine A Muldrew; Jayne Woodside; Michael R Stevenson; Usha Chakravarthy
Journal:  Ophthalmology       Date:  2013-03       Impact factor: 12.079

3.  A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E and beta carotene for age-related cataract and vision loss: AREDS report no. 9.

Authors: 
Journal:  Arch Ophthalmol       Date:  2001-10

4.  Ten-year follow-up of age-related macular degeneration in the age-related eye disease study: AREDS report no. 36.

Authors:  Emily Y Chew; Traci E Clemons; Elvira Agrón; Robert D Sperduto; John Paul Sangiovanni; Matthew D Davis; Frederick L Ferris
Journal:  JAMA Ophthalmol       Date:  2014-03       Impact factor: 7.389

5.  Secondary analyses of the effects of lutein/zeaxanthin on age-related macular degeneration progression: AREDS2 report No. 3.

Authors:  Emily Y Chew; Traci E Clemons; John Paul Sangiovanni; Ronald P Danis; Frederick L Ferris; Michael J Elman; Andrew N Antoszyk; Alan J Ruby; David Orth; Susan B Bressler; Gary E Fish; George Baker Hubbard; Michael L Klein; Suresh R Chandra; Barbara A Blodi; Amitha Domalpally; Thomas Friberg; Wai T Wong; Philip J Rosenfeld; Elvira Agrón; Cynthia A Toth; Paul S Bernstein; Robert D Sperduto
Journal:  JAMA Ophthalmol       Date:  2014-02       Impact factor: 7.389

Review 6.  Dietary omega-3 fatty acid and fish intake in the primary prevention of age-related macular degeneration: a systematic review and meta-analysis.

Authors:  Elaine W-T Chong; Andreas J Kreis; Tien Y Wong; Julie A Simpson; Robyn H Guymer
Journal:  Arch Ophthalmol       Date:  2008-06

Review 7.  Causes of vision loss worldwide, 1990-2010: a systematic analysis.

Authors:  Rupert R A Bourne; Gretchen A Stevens; Richard A White; Jennifer L Smith; Seth R Flaxman; Holly Price; Jost B Jonas; Jill Keeffe; Janet Leasher; Kovin Naidoo; Konrad Pesudovs; Serge Resnikoff; Hugh R Taylor
Journal:  Lancet Glob Health       Date:  2013-11-11       Impact factor: 26.763

8.  Treatment response to antioxidants and zinc based on CFH and ARMS2 genetic risk allele number in the Age-Related Eye Disease Study.

Authors:  Carl C Awh; Steven Hawken; Brent W Zanke
Journal:  Ophthalmology       Date:  2014-09-04       Impact factor: 12.079

9.  No clinically significant association between CFH and ARMS2 genotypes and response to nutritional supplements: AREDS report number 38.

Authors:  Emily Y Chew; Michael L Klein; Traci E Clemons; Elvira Agrón; Rinki Ratnapriya; Albert O Edwards; Lars G Fritsche; Anand Swaroop; Gonçalo R Abecasis
Journal:  Ophthalmology       Date:  2014-06-26       Impact factor: 12.079

10.  Nutritional risk factors for age-related macular degeneration.

Authors:  Lebriz Ersoy; Tina Ristau; Yara T Lechanteur; Moritz Hahn; Carel B Hoyng; Bernd Kirchhof; Anneke I den Hollander; Sascha Fauser
Journal:  Biomed Res Int       Date:  2014-07-03       Impact factor: 3.411
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  1 in total

Review 1.  Fluorescent Nanosystems for Drug Tracking and Theranostics: Recent Applications in the Ocular Field.

Authors:  Elide Zingale; Alessia Romeo; Salvatore Rizzo; Cinzia Cimino; Angela Bonaccorso; Claudia Carbone; Teresa Musumeci; Rosario Pignatello
Journal:  Pharmaceutics       Date:  2022-04-28       Impact factor: 6.525
  1 in total

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