Alex Gu1,2, Frank R Chen3, Aaron Z Chen3, Safa C Fassihi2, Savyasachi Thakkar4, Anthony S Unger5, Jiabin Liu6, Peter K Sculco1, Michael P Ast7. 1. Complex Joint Reconstruction Center, Department of Orthopaedic Surgery, Hospital for Special Surgery, 535 E 70th, St, New York, NY, 10021, USA. 2. The George Washington University School of Medicine, Department of Orthopaedic Surgery, 2300 I St NW, Washington, DC, 20052, USA. 3. Weill Cornell Medical College, 1300 York Ave, New York, NY, 10065, USA. 4. Department of Orthopaedic Surgery, MedStar Georgetown Orthopaedic Institute at Washington Hospital Center, 110 Irving St NW, Washington, DC, 20010, USA. 5. Gildenhorn Institute of Bone and Joint Health, Sibley Memorial Hospital, 5255 Loughboro Road NW, Washington, DC, 20016, USA. 6. Department of Anesthesiology, Hospital for Special Surgery, 535 East 70th St, New York, NY, 10021, USA. 7. Adult Reconstruction and Joint Replacement Division, Department of Orthopaedic Surgery, Hospital for Special Surgery, 535 E 70th, St, New York, NY, 10021, USA.
Abstract
INTRODUCTION: The purpose of this study is to investigate the relationship between preoperative hyponatremia and postoperative complications in aseptic revision hip and knee arthroplasty. METHODS: Aseptic revision arthroplasties from 2007 to 2016 were collected using a large, United States database. Patients were stratified into eunatremic and hyponatremic cohorts. Rates of complications were collected and analyzed. RESULTS: 25,517 surgeries were evaluated. Preoperative hyponatremia was independently associated with organ/space infections (OR= 2.316; p<0.001), postoperative blood transfusions (OR= 1.467; p<0.001), pneumonia (OR= 2.05; p =0.002), sepsis (OR= 2.533; p<0.001), extended length-of-stay (OR= 2.221; p<0.001), minor complications (OR= 1.549; p<0.001), wound complications (OR= 1.505; p=0.001), pulmonary complications (OR= 1.72; p=0.007), and sepsis complications (OR= 2.305; p<0.001). CONCLUSION: Hyponatremia is an independent risk factor for several postoperative complications in aseptic revision hip and knee arthroplasty.
INTRODUCTION: The purpose of this study is to investigate the relationship between preoperative hyponatremia and postoperative complications in aseptic revision hip and knee arthroplasty. METHODS: Aseptic revision arthroplasties from 2007 to 2016 were collected using a large, United States database. Patients were stratified into eunatremic and hyponatremic cohorts. Rates of complications were collected and analyzed. RESULTS: 25,517 surgeries were evaluated. Preoperative hyponatremia was independently associated with organ/space infections (OR= 2.316; p<0.001), postoperative blood transfusions (OR= 1.467; p<0.001), pneumonia (OR= 2.05; p =0.002), sepsis (OR= 2.533; p<0.001), extended length-of-stay (OR= 2.221; p<0.001), minor complications (OR= 1.549; p<0.001), wound complications (OR= 1.505; p=0.001), pulmonary complications (OR= 1.72; p=0.007), and sepsis complications (OR= 2.305; p<0.001). CONCLUSION: Hyponatremia is an independent risk factor for several postoperative complications in aseptic revision hip and knee arthroplasty.
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Authors: Aaron Z Chen; Alex Gu; Nicolas A Selemon; Jordan S Cohen; Chapman Wei; Haley Tornberg; Marc D Chodos; Joshua Campbell; Peter K Sculco Journal: Eur J Orthop Surg Traumatol Date: 2020-08-08