Literature DB >> 32051378

The Spinal Cord Uptake of Fluorodeoxyglucose in a Patient with Relapsing Polychondritis.

Ryoko Anada1, Tomohiro Hayashi1, Mamoru Yamamoto1, Yuji Nakatsuji1.   

Abstract

Entities:  

Keywords:  PET; meningoencephalitis; relapsing polychondritis; spinal cord

Year:  2020        PMID: 32051378      PMCID: PMC7303440          DOI: 10.2169/internalmedicine.3660-19

Source DB:  PubMed          Journal:  Intern Med        ISSN: 0918-2918            Impact factor:   1.271


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A 65-year-old man presented with a fever, chest pain, drowsiness, and urinary retention. A thickened tracheal wall was revealed by chest computed tomography, and high-intensity signals around the basal ganglia were observed on brain magnetic resonance imaging (MRI) (Picture 1, arrows). Antibodies against type II collagen tested positive later. Fluorodeoxyglucose-positron emission tomography (FDG-PET) revealed a strong FDG uptake in the whole spinal cord in addition to the tracheal wall and thyroid cartilage, although MRI did not show any abnormalities (Picture 2A, B, arrows). The diagnosis of meningoencephalitis accompanied by relapsing polychondritis (RP) was made. The patient received intravenous methylprednisolone followed by oral prednisolone. Thereafter, all of his symptoms except urinary dysfunction ameliorated. This was accompanied by a reduced FDG uptake (Picture 2C, arrow). Neurological involvement occurs in only 3% of patients with RP (1, 2). No previous studies have described such an abnormal FDG uptake in the spinal cord in a case of RP.
Picture 1.
Picture 2

The authors state that they have no Conflict of Interest (COI).
  2 in total

1.  Central nervous system involvement in relapsing polychondritis.

Authors:  Luzia Sampaio; Ligia Silva; Eva Mariz; Francisco Ventura
Journal:  Joint Bone Spine       Date:  2010-12       Impact factor: 4.929

Review 2.  Relapsing polychondritis.

Authors:  Xavier Puéchal; Benjamin Terrier; Luc Mouthon; Nathalie Costedoat-Chalumeau; Loïc Guillevin; Claire Le Jeunne
Journal:  Joint Bone Spine       Date:  2014-02-18       Impact factor: 4.929

  2 in total

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