Literature DB >> 32051153

Unintentional overdose of hyoscine hydrobromide in a young child.

Gerd Xuereb1, Thomas Calleja2, Janine Borg2, David Pace2.   

Abstract

A 4-year-old girl presented with confusion, ataxia and hallucinations 3 hours after an accidental overdose of 108 μg per kg of hyoscine hydrobromide (Kwells Kids). She was hypotensive and tachycardic at presentation. Investigations revealed QTc prolongation on ECG. The girl was admitted for observation overnight and was noted to have persistent visual and auditory hallucinations, which resolved without treatment. To our knowledge, this is the first reported case of an overdose of hyoscine hydrobromide at such a young age. Clinicians should be aware that unintentional ingestions in this age group may present with psychiatric manifestations. Hyoscine hydrobromide is easily accessible and available over the counter. It has serious consequences in overdose. Its packaging and appearance are attractive to young children making it susceptible to unintentional ingestions. We argue that its container should be altered to be more childproof. © BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  Safety; Toxicology; Unwanted effects/adverse reactions; paediatrics; pharmacology and therapeutics

Mesh:

Substances:

Year:  2020        PMID: 32051153      PMCID: PMC7035799          DOI: 10.1136/bcr-2019-234029

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


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