BACKGROUND: Prosthetic joint infection (PJI) is associated with significant morbidity, mortality, and costs. We developed a fast-track PJI care system using an infectious disease physician to work directly with the TJA service and coordinate in the treatment of PJI patients. We hypothesized that streamlined care of patients with hip and knee PJI decreases the length of the acute hospital stay without increasing the risk of complication or incorrect antibiotic selection. METHODS: A single-center retrospective chart review was performed for all patients treated operatively for PJI. A cohort of 78 fast-track patients was compared to 68 control patients treated before the implementation of the program. Hospital length of stay (LOS) and cases of antibiotic mismatch were primary outcomes. Secondary outcomes, including 90-day readmissions, reoperations, mortality, rate of reimplantation, and 12-month reimplant survival, were compared. Cox regressions were analyzed to assess the effects on LOS of patient demographics and the type of surgery performed. RESULTS: Average hospital LOS from infection surgery to discharge was significantly lower in the fast-track cohort (3.8 vs 5.7 days; P = .012). There were no episodes of antibiotic mismatch in the fast-track group vs 1 recorded episode in the control group. No significant differences were noted comparing 90-day complications, reimplantation rate, or 12-month reimplant survival rates. CONCLUSION: Through the utilization of an orthopedic-specific infectious disease physician, a fast-track PJI protocol can significantly shorten hospital LOS while remaining safe. Streamlining care pathways may help decrease the overall healthcare costs associated with treating PJI.
BACKGROUND: Prosthetic joint infection (PJI) is associated with significant morbidity, mortality, and costs. We developed a fast-track PJI care system using an infectious disease physician to work directly with the TJA service and coordinate in the treatment of PJI patients. We hypothesized that streamlined care of patients with hip and knee PJI decreases the length of the acute hospital stay without increasing the risk of complication or incorrect antibiotic selection. METHODS: A single-center retrospective chart review was performed for all patients treated operatively for PJI. A cohort of 78 fast-track patients was compared to 68 control patients treated before the implementation of the program. Hospital length of stay (LOS) and cases of antibiotic mismatch were primary outcomes. Secondary outcomes, including 90-day readmissions, reoperations, mortality, rate of reimplantation, and 12-month reimplant survival, were compared. Cox regressions were analyzed to assess the effects on LOS of patient demographics and the type of surgery performed. RESULTS: Average hospital LOS from infection surgery to discharge was significantly lower in the fast-track cohort (3.8 vs 5.7 days; P = .012). There were no episodes of antibiotic mismatch in the fast-track group vs 1 recorded episode in the control group. No significant differences were noted comparing 90-day complications, reimplantation rate, or 12-month reimplant survival rates. CONCLUSION: Through the utilization of an orthopedic-specific infectious disease physician, a fast-track PJI protocol can significantly shorten hospital LOS while remaining safe. Streamlining care pathways may help decrease the overall healthcare costs associated with treating PJI.
Authors: Gowrishankar Muthukrishnan; Christopher A Beck; John R Owen; Chao Xie; Stephen L Kates; John L Daiss Journal: J Orthop Res Date: 2020-12-25 Impact factor: 3.102
Authors: Gowrishankar Muthukrishnan; Alexandra Wallimann; Javier Rangel-Moreno; Karen L de Mesy Bentley; Maria Hildebrand; Karen Mys; H Mark Kenney; Eric T Sumrall; John L Daiss; Stephan Zeiter; R Geoff Richards; Edward M Schwarz; T Fintan Moriarty Journal: Front Immunol Date: 2021-03-18 Impact factor: 7.561
Authors: J R Owen; M P Campbell; M D Mott; C A Beck; C Xie; G Muthukrishnan; J L Daiss; E M Schwarz; S L Kates Journal: Eur Cell Mater Date: 2021-09-22 Impact factor: 3.942
Authors: Yugo Morita; Motoo Saito; Javier Rangel-Moreno; Anthony M Franchini; John R Owen; John C Martinez; John L Daiss; Karen L de Mesy Bentley; Stephen L Kates; Edward M Schwarz; Gowrishankar Muthukrishnan Journal: Bone Res Date: 2022-08-26 Impact factor: 13.362