Literature DB >> 32046834

Two-Stage Treatment for Total Knee Arthroplasty Infection Utilizing an Articulating Prefabricated Antibiotic Spacer.

Lucian C Warth1, Christopher J Hadley2, Eric L Grossman2.   

Abstract

Periprosthetic joint infection represents a serious complication following total knee arthroplasty. In the setting of chronic or age-indeterminate total knee arthroplasty infection, a 2-staged approach has been traditionally the preferred method of treatment over single-stage debridement and reimplantation debridement or debridement, antibiotics and implant retention. Two-stage is the preferred treatment method in North America and has demonstrated better overall success than the single stage techniques. Additionally, the 2-stage method is the preferred treatment for difficult to treat pathogens as well as in patients who have already undergone a previous revision procedure. An articulating prefabricated antibiotic spacer has entered the armamentarium of 2-stage revision knee surgery, and has demonstrated comparable results to custom and static spacers in terms of the primary goal of infection control. Importantly, the potential for enhanced mobility and function hold promise by safely providing a more "livable" knee during the convalescent period prior to definitive reimplantation.
Copyright © 2019 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  articulating prefabricated spacer; infection; periprosthetic joint infection (PJI); revision TKA; total knee arthroplasty (TKA); two-stage

Year:  2020        PMID: 32046834     DOI: 10.1016/j.arth.2019.10.049

Source DB:  PubMed          Journal:  J Arthroplasty        ISSN: 0883-5403            Impact factor:   4.757


  8 in total

1.  The Effect of Time Spent with a Dynamic Spacer on Clinical and Functional Outcomes in Two-Stage Revision Knee Arthroplasty.

Authors:  Fatih Golgelioglu; Sinan Oguzkaya; Abdulhamit Misir; Ahmet Guney
Journal:  Indian J Orthop       Date:  2020-09-02       Impact factor: 1.251

2.  Comparison of dynamic and static spacers for the treatment of infections following total knee replacement: a systematic review and meta-analysis.

Authors:  Jiasheng Tao; Zijian Yan; Bin Pu; Ming Chen; Xiaorong Hu; Hang Dong
Journal:  J Orthop Surg Res       Date:  2022-07-15       Impact factor: 2.677

3.  Intra-articular versus systemic vancomycin for the treatment of periprosthetic joint infection after debridement and spacer implantation in a rat model.

Authors:  Jian Wei; Kai Tong; Hui Wang; Yinxian Wen; Liaobin Chen
Journal:  Bone Joint Res       Date:  2022-06       Impact factor: 4.410

4.  Successful Two-Stage Exchange Arthroplasty for Periprosthetic Infection Following Total Knee Arthroplasty: The Impact of Timing on Eradication of Infection.

Authors:  Ines Vielgut; Gerold Schwantzer; Andreas Leithner; Patrick Sadoghi; Uldis Berzins; Mathias Glehr
Journal:  Int J Med Sci       Date:  2021-01-01       Impact factor: 3.738

5.  Comparing the Efficacy of Articulating Spacers in Two-Stage Revision for Periprosthetic Joint Infection Following Total Knee Arthroplasty: All-Cement Spacers vs Sterilized Replanted Metal-Polyethylene Spacers.

Authors:  Zhixuan Fei; Zian Zhang; Yingzhen Wang; Haining Zhang; Shuai Xiang
Journal:  Int J Gen Med       Date:  2022-03-24

6.  Does spiked tibial cement spacer reduce spacer-related problems in two-stage revision total knee arthroplasty for infection?

Authors:  Kwang-Hwan Jung; Chae-Chil Lee; Tae-Hoon Kim; Jung-Won Han; Ki-Bong Park
Journal:  Int Orthop       Date:  2022-05-18       Impact factor: 3.479

Review 7.  A review of current practices in periprosthetic joint infection debridement and revision arthroplasty.

Authors:  Humza M Mian; Joseph G Lyons; Joshua Perrin; Andrew W Froehle; Anil B Krishnamurthy
Journal:  Arthroplasty       Date:  2022-09-01

8.  Application of 3D Printing-Assisted Articulating Spacer in Two-Stage Revision Surgery for Periprosthetic Infection after Total Knee Arthroplasty: A Retrospective Observational Study.

Authors:  Lingtong Kong; Jiawei Mei; Wufei Ge; Xiansheng Jin; Xiaoxuan Chen; Xianzuo Zhang; Chen Zhu
Journal:  Biomed Res Int       Date:  2021-02-08       Impact factor: 3.411

  8 in total

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