Literature DB >> 32045170

Vitiligo-like lesions located over In-transit metastases of malignant melanoma as a clinical marker of complete response to pembrolizumab.

Tamara Gracia-Cazaña1, Esteban Padgett, Alba Hernández-García, María Pilar Sánchez-Salas.   

Abstract

Anti-programmed cell death (PD)-1 therapies in metastatic tumors have a high incidence of immune adverse events, including cutaneous manifestations such as vitiligo-like lesions. This side effect is associated with increased survival and it is a clinical marker of response to treatment. This case report is a graphic representation of the appearance of vitiligo-like lesions over in-transit metastases of malignant melanoma linked to a complete response to treatment with pembrolizumab.

Entities:  

Year:  2019        PMID: 32045170

Source DB:  PubMed          Journal:  Dermatol Online J        ISSN: 1087-2108


  2 in total

Review 1.  Treatment of patients with cancer using PD‑1/PD‑L1 antibodies: Adverse effects and management strategies (Review).

Authors:  Guangshun Sun; Hanyuan Liu; Xuesong Shi; Pengyu Tan; Weiwei Tang; Xin Chen; Guoqiang Sun; Weijun Yang; Xiangyi Kong; Zhiying Zheng; Hongyong Cao; Guoqiang Shao
Journal:  Int J Oncol       Date:  2022-04-29       Impact factor: 5.884

2.  [Development of destructive thyroiditis and diabetes mellitus after three injections of pembrolizumab for skin melanoma].

Authors:  A A Glibka; G A Mel Nichenko; M S Mikhina; N V Mazurina; G Yu Kharkevich
Journal:  Probl Endokrinol (Mosk)       Date:  2021-02-09
  2 in total

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