Histopathological determinants of autofluorescence patterns in oral carcinoma.

Current gold standard for oral squamous cell carcinoma (OSCC) and potentially malignant disorders (PMDs) diagnosis is histopathologic analysis, usually performed on preoperative incisional biopsies. Several tools have been proposed in order to improve the diagnostic accuracy and to possibly help the identification of most suspicious areas of dysplastic or neoplastic alterations (Holmstrup, Vedtofte, Reibel & Stoltze, 2007). However, the use of such diagnostic aids is associated to low accuracy (Giovannacci, Vescovi, Manfredi, & Meleti, 2016). This article is protected by copyright. All rights reserved.