Literature DB >> 32042611

Barriers and solutions to finding rifampicin-resistant tuberculosis cases in older children and adolescents.

E Mohr-Holland1,2, I Apolisi1, A Reuter1, V de Azevedo3, J Hill4, S Matthee5, J A Seddon6,7, P Isaakidis2, J Furin8, L Trivino-Duran1.   

Abstract

Little is known about the barriers to post-exposure management of rifampicin-resistant tuberculosis (RR-TB) in older children and adolescents. We report on implementation lessons from a pilot programme targeting household-exposed individuals aged 6-18 years in Khayelitsha, South Africa. Barriers included misperceptions regarding risk of exposure, multiple research and implementation stakeholders, additional workload for an overburdened healthcare system, logistical issues faced by families, and insufficient human and financial resources. Solutions to these barriers are possible, but creativity and persistence are required. Our experience can guide others looking to roll-out care for children and adolescents exposed to RR-TB.
© 2019 The Union.

Entities:  

Keywords:  Khayelitsha; RR-TB; South Africa; post-exposure management; vulnerable populations

Year:  2019        PMID： 32042611      PMCID： PMC6945730          DOI： 10.5588/pha.19.0050

Source DB:  PubMed          Journal:  Public Health Action        ISSN： 2220-8372


  5 in total

1.  Active case finding in tuberculosis-affected households: time to scale up.

Authors:  Tom Wingfield; Stéphane Verguet
Journal:  Lancet Glob Health       Date:  2019-03       Impact factor: 26.763

Review 2.  Tuberculosis in children.

Authors:  Carlos M Perez-Velez; Ben J Marais
Journal:  N Engl J Med       Date:  2012-07-26       Impact factor: 91.245

3.  High tuberculosis prevalence in children exposed at home to drug-resistant tuberculosis.

Authors:  F Amanullah; M Ashfaq; S Khowaja; A Parekh; N Salahuddin; I Lotia-Farrukh; A J Khan; M C Becerra
Journal:  Int J Tuberc Lung Dis       Date:  2014-05       Impact factor: 2.373

4.  Map the gap: missing children with drug-resistant tuberculosis.

Authors:  C M Yuen; C A Rodriguez; S Keshavjee; M C Becerra
Journal:  Public Health Action       Date:  2015-03-21

5.  Improving active case finding for tuberculosis in South Africa: informing innovative implementation approaches in the context of the Kharitode trial through formative research.

Authors:  Deanna Kerrigan; Nora West; Carrie Tudor; Colleen F Hanrahan; Limakatso Lebina; Reginah Msandiwa; Lesego Mmolawa; Neil Martinson; David Dowdy
Journal:  Health Res Policy Syst       Date:  2017-05-30
  5 in total
  1 in total

1.  Pediatric delamanid treatment for children with rifampicin-resistant TB.

Authors:  N Tyeku; I Apolisi; J Daniels; B Beko; B Memani; L Cengani; S Fatshe; N Gumede; K Joseph; S Mathee; J Furin; C Maugans; H Cox; A Reuter
Journal:  Int J Tuberc Lung Dis       Date:  2022-10-01       Impact factor: 3.427
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.