Literature DB >> 3204104

Aqueous extract of betel-nut of north-east India induces DNA-strand breaks and enhances rate of cell proliferation in vitro. Effects of betel-nut extract in vitro.

K K Wary1, R N Sharan.   

Abstract

An aqueous extract of betel-nut has been found to be able to induce strand breaks in DNA of mouse kidney cells in vitro. It has been also found to be able to enhance the rate of cell division at a dose of 100 micrograms/ml while a higher dose of 250 micrograms/ml was extremely toxic to the cells. Compared with arecoline (10 micrograms/ml), the aqueous extract of betel-nut seems to be a more potent carcinogen to mouse kidney cells in vitro.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 3204104     DOI： 10.1007/bf00398180

Source DB:  PubMed          Journal:  J Cancer Res Clin Oncol        ISSN： 0171-5216            Impact factor:   4.553


  11 in total

1.  The rate of strand separation in alkali of DNA of irradiated mammalian cells.

Authors:  B Rydberg
Journal:  Radiat Res       Date:  1975-02       Impact factor: 2.841

2.  Tobacco habits other than smoking; betel-quid and areca-nut chewing; and some related nitrosamines. IARC Working Group. Lyon, 23-30 October 1984.

Authors: 
Journal:  IARC Monogr Eval Carcinog Risk Chem Hum       Date:  1985-09

3.  Correlation of mutagenicity and tumorigenicity of betel quid and its ingredients.

Authors:  L P Shirname; M M Menon; J Nair; S V Bhide
Journal:  Nutr Cancer       Date:  1983       Impact factor: 2.900

4.  Betel nuts, arecaidine, and oral cancer.

Authors:  J Ashby; J A Styles; E Boyland
Journal:  Lancet       Date:  1979-01       Impact factor: 79.321

5.  Elevated frequency of micronucleated cells in the buccal mucosa of individuals at high risk for oral cancer: betel quid chewers.

Authors:  H F Stich; W Stich; B B Parida
Journal:  Cancer Lett       Date:  1982 Nov-Dec       Impact factor: 8.679

6.  Morphological transformation, sister chromatid exchange and mutagenesis assay of betel constituents.

Authors:  K Umezawa; S Fujie; M Sawamura; T Matsushima; Y Katoh; M Tanaka; S Takayama
Journal:  Toxicol Lett       Date:  1981-04       Impact factor: 4.372

7.  Chromosome-damaging activity of saliva of betel nut and tobacco chewers.

Authors:  H F Stich; W Stich
Journal:  Cancer Lett       Date:  1982 Mar-Apr       Impact factor: 8.679

Review 8.  Areca nut: a review.

Authors:  K N Arjungi
Journal:  Arzneimittelforschung       Date:  1976

9.  Chromosome-breaking ability of arecoline, a major betel-nut alkaloid, in mouse bone-marrow cells in vivo.

Authors:  G B Panigrahi; A R Rao
Journal:  Mutat Res       Date:  1982-02       Impact factor: 2.433

10.  Betel, tobacco, and cancer of the mouth.

Authors:  C S MUIR; R KIRK
Journal:  Br J Cancer       Date:  1960-12       Impact factor: 7.640
View more
  9 in total

1.  In vitro genotoxic effects of areca nut extract and arecoline.

Authors:  B J Dave; A H Trivedi; S G Adhvaryu
Journal:  J Cancer Res Clin Oncol       Date:  1992       Impact factor: 4.553

2.  Cyclin d1 gene expression in oral mucosa of tobacco chewers"-an immunohistochemical study.

Authors:  Maharudrappa Basnaker; Srikala Sp; Satish Bnvs
Journal:  J Clin Diagn Res       Date:  2014-05-15

Review 3.  Genetic toxicology and toxicokinetics of arecoline and related areca nut compounds: an updated review.

Authors:  Nuno G Oliveira; Daniela L Ramos; Ricardo Jorge Dinis-Oliveira
Journal:  Arch Toxicol       Date:  2020-10-24       Impact factor: 5.153

4.  Betel nut (Areca catechu) consumption and the induction of glucose intolerance in adult CD1 mice and in their F1 and F2 offspring.

Authors:  B J Boucher; S W Ewen; J M Stowers
Journal:  Diabetologia       Date:  1994-01       Impact factor: 10.122

5.  Tobacco harm reduction: an alternative cessation strategy for inveterate smokers.

Authors:  Brad Rodu; William T Godshall
Journal:  Harm Reduct J       Date:  2006-12-21

6.  Phenotypic Expression of Oral Fibroblasts Derived from Oral Submucous Fibrosis: An Assay through Cell Culture.

Authors:  Abhishek Banerjee; Mathew O Mampilly; V V Kamath; Vijayaraghavan Athreya; Vijayalakshmi Kotrashetti; Kumar Chandan Srivastava; Deepti Shrivastava
Journal:  J Pharm Bioallied Sci       Date:  2021-11-10

Review 7.  The health impact of smokeless tobacco products: a systematic review.

Authors:  C Hajat; E Stein; L Ramstrom; S Shantikumar; R Polosa
Journal:  Harm Reduct J       Date:  2021-12-04

Review 8.  Association of betel nut with carcinogenesis: revisit with a clinical perspective.

Authors:  Rajeshwar N Sharan; Ravi Mehrotra; Yashmin Choudhury; Kamlesh Asotra
Journal:  PLoS One       Date:  2012-08-13       Impact factor: 3.240

9.  Promoter-associated DNA methylation & expression profiling of genes (FLT 3, EPB41L3 & SFN) in patients with oral squamous cell carcinoma in the Khasi & Jaintia population of Meghalaya, India.

Authors:  Shngainlang Khongsti; Brian Neizekhotuo Shunyu; Srimoyee Ghosh
Journal:  Indian J Med Res       Date:  2019-12       Impact factor: 2.375
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.