BACKGROUND: The primary purpose of this study was to examine the feasibility and acceptability of participation in a randomized waitlist-controlled intervention of mindfulness-based stress reduction (MBSR) in a young adult cancer sample. A secondary aim was to examine patterns of change in patient reported outcomes (PROs) of physical, social, and emotional functioning. METHODS:Participants were enrolled at a large Midwestern comprehensive cancer center and randomized toMBSR or a waitlist control. Feasibility and acceptability were examined through enrollment metrics and a survey. PROs were gathered at baseline, 8-weeks, and 16-weeks. Descriptive statistics and mixed models were used in analyses. RESULTS:Of 597 eligible participants, 151 (26.5%) consented from which 126 (83.4%) completed baseline measures. Sixty-seven participants were randomized to MBSR, and 59 to the waitlist. Immediately following MBSR, the majority of respondents (72%-78%) reported their experience with mindfulness was very logical and useful to increasing their wellbeing. Compared to waitlist members, MBSR participant's scores on PROs improved in expected directions. CONCLUSIONS: Our findings suggest that recruitment for an intensive, in-person, multi-week supportive intervention can be challenging with young adults with cancer, similar to other cancer survivor populations; however once enrolled, feasibility and acceptability of MBSR was supported. Further, initial evidence on the role of MBSR on short-term changes in select PROs with this population was also demonstrated.
RCT Entities:
BACKGROUND: The primary purpose of this study was to examine the feasibility and acceptability of participation in a randomized waitlist-controlled intervention of mindfulness-based stress reduction (MBSR) in a young adult cancer sample. A secondary aim was to examine patterns of change in patient reported outcomes (PROs) of physical, social, and emotional functioning. METHODS:Participants were enrolled at a large Midwestern comprehensive cancer center and randomized to MBSR or a waitlist control. Feasibility and acceptability were examined through enrollment metrics and a survey. PROs were gathered at baseline, 8-weeks, and 16-weeks. Descriptive statistics and mixed models were used in analyses. RESULTS: Of 597 eligible participants, 151 (26.5%) consented from which 126 (83.4%) completed baseline measures. Sixty-seven participants were randomized to MBSR, and 59 to the waitlist. Immediately following MBSR, the majority of respondents (72%-78%) reported their experience with mindfulness was very logical and useful to increasing their wellbeing. Compared to waitlist members, MBSR participant's scores on PROs improved in expected directions. CONCLUSIONS: Our findings suggest that recruitment for an intensive, in-person, multi-week supportive intervention can be challenging with young adults with cancer, similar to other cancer survivor populations; however once enrolled, feasibility and acceptability of MBSR was supported. Further, initial evidence on the role of MBSR on short-term changes in select PROs with this population was also demonstrated.
Authors: Catherine Benedict; Bridgette Thom; Danielle N Friedman; Elaine Pottenger; Nirupa Raghunathan; Joanne F Kelvin Journal: Support Care Cancer Date: 2018-02-01 Impact factor: 3.603
Authors: Peter F Coccia; Jessica Altman; Smita Bhatia; Scott C Borinstein; Joseph Flynn; Suzanne George; Robert Goldsby; Robert Hayashi; Mary S Huang; Rebecca H Johnson; Lynda Kwon Beaupin; Michael P Link; Kevin C Oeffinger; Kathleen M Orr; Alberto S Pappo; Damon Reed; Holly L Spraker; Deborah A Thomas; Margaret von Mehren; Daniel S Wechsler; Kimberly F Whelan; Bradley J Zebrack; Hema Sundar; Dorothy A Shead Journal: J Natl Compr Canc Netw Date: 2012-09 Impact factor: 11.908
Authors: Catherine Benedict; Katherine L Dauber-Decker; Jennifer S Ford; D'Arcy King; David Spiegel; Lidia Schapira; Pamela Simon; Michael Diefenbach Journal: JMIR Cancer Date: 2022-05-31
Authors: Laura B Oswald; Rina S Fox; Karly M Murphy; John M Salsman; Stacy D Sanford; Thomas W McDade; David E Victorson Journal: Int J Behav Med Date: 2022-01-20
Authors: Helen Mizrach; Brett Goshe; Elyse R Park; Christopher Recklitis; Joseph A Greer; Yuchiao Chang; Natasha Frederick; Annah Abrams; Mary D Tower; Emily A Walsh; Mary Huang; Lisa Kenney; Alan Homans; Karen Miller; John Denninger; Ghazala Naheed Usmani; Jeffrey Peppercorn; Giselle K Perez Journal: JMIR Res Protoc Date: 2022-01-26