Literature DB >> 32039286

NUDT15 genotyping in Caucasian patients can help to optimise thiopurine treatment in patients with inflammatory bowel disease.

Marieke J H Coenen1.   

Abstract

Entities:  

Year:  2019        PMID： 32039286      PMCID： PMC6987327          DOI： 10.21037/tgh.2019.11.09

Source DB:  PubMed          Journal:  Transl Gastroenterol Hepatol        ISSN： 2415-1289


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  23 in total

1.  NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity.

Authors:  Takaya Moriyama; Rina Nishii; Virginia Perez-Andreu; Wenjian Yang; Federico Antillon Klussmann; Xujie Zhao; Ting-Nien Lin; Keito Hoshitsuki; Jacob Nersting; Kentaro Kihira; Ute Hofmann; Yoshihiro Komada; Motohiro Kato; Robert McCorkle; Lie Li; Katsuyoshi Koh; Cesar Rolando Najera; Shirley Kow-Yin Kham; Tomoya Isobe; Zhiwei Chen; Edwynn Kean-Hui Chiew; Deepa Bhojwani; Cynthia Jeffries; Yan Lu; Matthias Schwab; Hiroto Inaba; Ching-Hon Pui; Mary V Relling; Atsushi Manabe; Hiroki Hori; Kjeld Schmiegelow; Allen E J Yeoh; William E Evans; Jun J Yang
Journal:  Nat Genet       Date:  2016-02-15       Impact factor: 38.330

2.  The efficacy of azathioprine for the treatment of inflammatory bowel disease: a 30 year review.

Authors:  A G Fraser; T R Orchard; D P Jewell
Journal:  Gut       Date:  2002-04       Impact factor: 23.059

3.  Inherited NUDT15 variant is a genetic determinant of mercaptopurine intolerance in children with acute lymphoblastic leukemia.

Authors:  Jun J Yang; Wendy Landier; Wenjian Yang; Chengcheng Liu; Lindsey Hageman; Cheng Cheng; Deqing Pei; Yanjun Chen; Kristine R Crews; Nancy Kornegay; F Lennie Wong; William E Evans; Ching-Hon Pui; Smita Bhatia; Mary V Relling
Journal:  J Clin Oncol       Date:  2015-01-26       Impact factor: 44.544

4.  Preclinical evaluation of NUDT15-guided thiopurine therapy and its effects on toxicity and antileukemic efficacy.

Authors:  Rina Nishii; Takaya Moriyama; Laura J Janke; Wenjian Yang; Chase C Suiter; Ting-Nien Lin; Lie Li; Kentaro Kihira; Hidemi Toyoda; Ute Hofmann; Matthias Schwab; Masatoshi Takagi; Tomohiro Morio; Atsushi Manabe; Shirley Kham; Nan Jiang; Karen R Rabin; Motohiro Kato; Katsuyoshi Koh; Allen Eng-Juh Yeoh; Hiroki Hori; Jun J Yang
Journal:  Blood       Date:  2018-03-23       Impact factor: 22.113

5.  6-Mercaptopurine in the management of inflammatory bowel disease: short- and long-term toxicity.

Authors:  D H Present; S J Meltzer; M P Krumholz; A Wolke; B I Korelitz
Journal:  Ann Intern Med       Date:  1989-10-15       Impact factor: 25.391

6.  Influences of thiopurine methyltransferase genotype and activity on thiopurine-induced leukopenia in Korean patients with inflammatory bowel disease: a retrospective cohort study.

Authors:  Jae Hak Kim; Jae Hee Cheon; Seong Soo Hong; Chang Soo Eun; Jeong-Sik Byeon; Sung Yi Hong; Bo-Young Kim; Soon-Ho Kwon; Seung Won Kim; Dong Soo Han; Suk-Kyun Yang; Won Ho Kim
Journal:  J Clin Gastroenterol       Date:  2010 Nov-Dec       Impact factor: 3.062

7.  Genomewide Approach Validates Thiopurine Methyltransferase Activity Is a Monogenic Pharmacogenomic Trait.

Authors:  C Liu; W Yang; D Pei; C Cheng; C Smith; W Landier; L Hageman; Y Chen; J J Yang; K R Crews; N Kornegay; S E Karol; F L Wong; S Jeha; J T Sandlund; R C Ribeiro; J E Rubnitz; M L Metzger; C-H Pui; W E Evans; S Bhatia; M V Relling
Journal:  Clin Pharmacol Ther       Date:  2016-11-18       Impact factor: 6.875

8.  Functional characterization of 23 allelic variants of thiopurine S-methyltransferase gene (TPMT*2 - *24).

Authors:  Shuta Ujiie; Takamitsu Sasaki; Michinao Mizugaki; Masaaki Ishikawa; Masahiro Hiratsuka
Journal:  Pharmacogenet Genomics       Date:  2008-10       Impact factor: 2.089

9.  A common missense variant in NUDT15 confers susceptibility to thiopurine-induced leukopenia.

Authors:  Suk-Kyun Yang; Myunghee Hong; Jiwon Baek; Hyunchul Choi; Wanting Zhao; Yusun Jung; Talin Haritunians; Byong Duk Ye; Kyung-Jo Kim; Sang Hyoung Park; Soo-Kyung Park; Dong-Hoon Yang; Marla Dubinsky; Inchul Lee; Dermot P B McGovern; Jianjun Liu; Kyuyoung Song
Journal:  Nat Genet       Date:  2014-08-10       Impact factor: 38.330

10.  Pharmacogene Variation Consortium Gene Introduction: NUDT15.

Authors:  Jun J Yang; Michelle Whirl-Carrillo; Stuart A Scott; Amy J Turner; Matthias Schwab; Yoichi Tanaka; Guilherme Suarez-Kurtz; Elke Schaeffeler; Teri E Klein; Neil A Miller; Andrea Gaedigk
Journal:  Clin Pharmacol Ther       Date:  2018-12-04       Impact factor: 6.875
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  2 in total

1.  Intestinal mRNA expression profile and bioinformatics analysis in a methamphetamine-induced mouse model of inflammatory bowel disease.

Authors:  Jiaxue Sun; Fengrong Chen; Cheng Chen; Zherui Zhang; Zunyue Zhang; Weiwei Tian; Juehua Yu; Kunhua Wang
Journal:  Ann Transl Med       Date:  2020-12

Review 2.  Thiopurine pharmacogenomics and pregnancy in inflammatory bowel disease.

Authors:  Akira Andoh; Masahiro Kawahara; Takayuki Imai; Goichi Tatsumi; Osamu Inatomi; Yoichi Kakuta
Journal:  J Gastroenterol       Date:  2021-07-21       Impact factor: 7.527
  2 in total

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