Literature DB >> 32031263

Characterization of microMOSFET detectors for in vivo dosimetry in high-dose-rate brachytherapy with 192 Ir.

Samuel Ruiz-Arrebola1, Rosa Fabregat-Borrás1, Eduardo Rodríguez1, Manuel Fernández-Montes1, Mercedes Pérez-Macho1, María Ferri1, Ana García1, Juan Cardenal1, María T Pacheco1, Javier Anchuelo1, Ana M Tornero-López2, Pedro J Prada1, Damián Guirado3,4.   

Abstract

PURPOSE: The objective of this study was to characterize the Best Medical Canada microMOSFET detectors for their application in in vivo dosimetry for high-dose-rate brachytherapy (HDRBT) with 192 Ir. We also developed a mathematical model to correct dependencies under the measurement conditions of these detectors.
METHODS: We analyzed the linearity, reproducibility, and interdetector variability and studied the microMOSFET response dependence on temperature, source-detector distance, and angular orientation of the receptor with respect to the source. The correction model was applied to 19 measurements corresponding to five simulated treatments in a custom phantom specifically designed for this purpose.
RESULTS: The detectors (high bias applied in all measurements) showed excellent linearity up to 160 Gy. The response dependence on source-detector distance varied by (8.65 ± 0.06)% (k = 1) for distances between 1 and 7 cm, and the variation with temperature was (2.24 ± 0.05)% (k = 1) between 294 and 310 K. The response difference due to angular dependence can reach (10.3 ± 1.3)% (k = 1). For the set of measurements analyzed, regarding angular dependences, the mean difference between administered and measured doses was -4.17% (standard deviation of 3.4%); after application of the proposed correction model, the mean difference was -0.1% (standard deviation of 2.2%). For the treatments analyzed, the average difference between calculations and measures was 4.7% when only the calibration coefficient was used, but it is reduced to 0.9% when the correction model is applied.
CONCLUSION: Important response dependencies of microMOSFET detectors used for in vivo dosimetry in HDRBT treatments, especially the angular dependence, can be adequately characterized by a correction model that increases the accuracy of this system in clinical applications.
© 2020 American Association of Physicists in Medicine.

Entities:  

Keywords:  MOSFET; brachytherapy; correction model; in vivo dosimetry

Year:  2020        PMID: 32031263     DOI: 10.1002/mp.14080

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  1 in total

1.  Light-Dependent Resistors as Dosimetric Sensors in Radiotherapy.

Authors:  Juan Román-Raya; Isidoro Ruiz-García; Pablo Escobedo; Alberto J Palma; Damián Guirado; Miguel A Carvajal
Journal:  Sensors (Basel)       Date:  2020-03-11       Impact factor: 3.576

  1 in total

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