Literature DB >> 32030366

Pulmonary mucormycosis developed during acute myelogenous leukemia and successfully treated by surgical resection before blood stem cell transplantation.

Kentaro Miura1, Nobutaka Kobayashi1, Ichiro Ito2, Nozomu Uematsu3, Toshimitsu Ueki3, Yuta Nakano4, Hikaru Kobayashi3.   

Abstract

Pulmonary mucormycosis is relatively rare and occurs in immunosuppressed patients, for example, individuals with hematologic malignancies such as leukemia. As pulmonary mucormycosis increases rapidly and is often fatal, appropriate treatment including surgical resection is necessary. We report a patient with pulmonary mucormycosis and acute myelogenous leukemia for which antifungal drugs were invalid. After rapid surgical resection, the patient was administered a peripheral blood stem cell transplantation. In conclusion, we emphasize that patients with pulmonary mucormycosis undergoing leukemia treatment should be considered for rapid surgical treatment if the infected lesion is limited, as overcoming this acute infection increases their chance to undergo hematopoietic stem cell transplantation and potential for long-term survival. 2019 AME Case Reports. All rights reserved.

Entities:  

Keywords:  Pulmonary mucormycosis; leukemia; peripheral blood stem cell transplantation; surgical resection

Year:  2019        PMID: 32030366      PMCID: PMC6987314          DOI: 10.21037/acr.2019.11.02

Source DB:  PubMed          Journal:  AME Case Rep        ISSN: 2523-1995


  7 in total

Review 1.  Epidemiology and outcome of zygomycosis: a review of 929 reported cases.

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Journal:  Clin Infect Dis       Date:  2005-07-29       Impact factor: 9.079

Review 2.  Epidemiology and clinical manifestations of mucormycosis.

Authors:  George Petrikkos; Anna Skiada; Olivier Lortholary; Emmanuel Roilides; Thomas J Walsh; Dimitrios P Kontoyiannis
Journal:  Clin Infect Dis       Date:  2012-02       Impact factor: 9.079

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Journal:  Arch Intern Med       Date:  1999-06-28

4.  Pulmonary mucormycosis: clinical features and outcomes.

Authors:  Erica Lin; Teng Moua; Andrew H Limper
Journal:  Infection       Date:  2017-02-20       Impact factor: 3.553

Review 5.  Pulmonary mucormycosis: results of medical and surgical therapy.

Authors:  M Tedder; J A Spratt; M P Anstadt; S S Hegde; S D Tedder; J E Lowe
Journal:  Ann Thorac Surg       Date:  1994-04       Impact factor: 4.330

6.  Pulmonary zygomycosis: CT appearance.

Authors:  D A Jamadar; E A Kazerooni; B D Daly; C S White; B H Gross
Journal:  J Comput Assist Tomogr       Date:  1995 Sep-Oct       Impact factor: 1.826

7.  Proven invasive pulmonary mucormycosis successfully treated with amphotericin B and surgery in patient with acute myeloblastic leukemia: a case report.

Authors:  Ana Vidovic; Valentina Arsic-Arsenijevic; Dragica Tomin; Irena Djunic; Radoslav Jakovic; Zlatibor Loncar; Aleksandra Barac
Journal:  J Med Case Rep       Date:  2013-12-03
  7 in total

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