Literature DB >> 32030099

Nebuliser cleaning and disinfection practice in the home among patients with cystic fibrosis.

Mary MacFarlane1, Lesley Carson2, Amanda Crossan2, Jane Bell1, John E Moore2,3, B Cherie Millar2,3.   

Abstract

BACKGROUND: Nebulised delivery of different classes of drugs is of fundamental importance in therapeutic regimens relating to both the management of disease progression in cystic fibrosis disease and its associated complications. The aim of this study was to determine if current nebuliser hygiene practices in the home environment by paediatric and adult cystic fibrosis populations are appropriate to ensure appropriate infection control and prevention measures have been addressed.
METHODS: An Audit Questionnaire Study was completed with adult cystic fibrosis patients (n=20) or with parents of cystic fibrosis children (n=24), through a healthcare professional interview on a one-to-one basis, during either a home visit or during patient/parent attendance at cystic fibrosis clinic.
RESULTS: Hygienic practices relating to nebuliser care varied, with paediatric carers more likely to clean and disinfect their devices. This study suggests there is much variation and confusion with regard to how to clean and disinfect nebulisers, as well as who is responsible for delivering this advice.
CONCLUSION: The adult cystic fibrosis community in particular needs to be educated on practicalities associated with nebuliser hygiene and the reasons why this is important. Furthermore, to date there is a lack of a universally recommended guideline suitable for all types of cystic fibrosis nebulisers that all relevant pharmaceutical manufacturers advocate.
© The Author(s) 2019.

Entities:  

Keywords:  Contamination; Pseudomonas aeruginosa; cystic fibrosis (CF); disinfection; hygiene; nebuliser

Year:  2019        PMID: 32030099      PMCID: PMC6978570          DOI: 10.1177/1757177419855603

Source DB:  PubMed          Journal:  J Infect Prev        ISSN: 1757-1782


  25 in total

Review 1.  A European regulatory perspective on cystic fibrosis: current treatments, trends in drug development and translational challenges for CFTR modulators.

Authors:  Stefano Ponzano; Giulia Nigrelli; Laura Fregonese; Irmgard Eichler; Fabio Bertozzi; Tiziano Bandiera; Luis J V Galietta; Marisa Papaluca
Journal:  Eur Respir Rev       Date:  2018-04-13

2.  Baby bottle steam sterilizers disinfect home nebulizers inoculated with bacterial respiratory pathogens.

Authors:  Dana Towle; Deborah A Callan; Patricia A Farrel; Marie E Egan; Thomas S Murray
Journal:  J Cyst Fibros       Date:  2012-12-23       Impact factor: 5.482

3.  Home-use nebulizers: a potential primary source of Burkholderia cepacia and other colistin-resistant, gram-negative bacteria in patients with cystic fibrosis.

Authors:  G R Hutchinson; S Parker; J A Pryor; F Duncan-Skingle; P N Hoffman; M E Hodson; M E Kaufmann; T L Pitt
Journal:  J Clin Microbiol       Date:  1996-03       Impact factor: 5.948

Review 4.  ECFS best practice guidelines: the 2018 revision.

Authors:  Carlo Castellani; Alistair J A Duff; Scott C Bell; Harry G M Heijerman; Anne Munck; Felix Ratjen; Isabelle Sermet-Gaudelus; Kevin W Southern; Jurg Barben; Patrick A Flume; Pavla Hodková; Nataliya Kashirskaya; Maya N Kirszenbaum; Sue Madge; Helen Oxley; Barry Plant; Sarah Jane Schwarzenberg; Alan R Smyth; Giovanni Taccetti; Thomas O F Wagner; Susan P Wolfe; Pavel Drevinek
Journal:  J Cyst Fibros       Date:  2018-03-03       Impact factor: 5.482

Review 5.  Cystic fibrosis: a clinical view.

Authors:  Carlo Castellani; Baroukh M Assael
Journal:  Cell Mol Life Sci       Date:  2016-10-05       Impact factor: 9.261

6.  Occurrence of Pseudomonas aeruginosa in waters: implications for patients with cystic fibrosis (CF).

Authors:  S Caskey; J Stirling; J E Moore; J C Rendall
Journal:  Lett Appl Microbiol       Date:  2018-04-16       Impact factor: 2.858

Review 7.  Ion Channel Modulators in Cystic Fibrosis.

Authors:  Martina Gentzsch; Marcus A Mall
Journal:  Chest       Date:  2018-05-08       Impact factor: 9.410

8.  High treatment burden in adults with cystic fibrosis: challenges to disease self-management.

Authors:  Gregory S Sawicki; Deborah E Sellers; Walter M Robinson
Journal:  J Cyst Fibros       Date:  2008-10-26       Impact factor: 5.482

9.  Changes in performance of the Pari eFlow rapid and Pari LC Plus during 6 months use by CF patients.

Authors:  Bart L Rottier; Cyril J P van Erp; Tanya S Sluyter; Harry G M Heijerman; Henderik W Frijlink; Anne H de Boer
Journal:  J Aerosol Med Pulm Drug Deliv       Date:  2009-09       Impact factor: 2.849

10.  The top 10 research priorities in cystic fibrosis developed by a partnership between people with CF and healthcare providers.

Authors:  Nicola J Rowbotham; Sherie Smith; Paul A Leighton; Oli C Rayner; Katie Gathercole; Zoe C Elliott; Edward F Nash; Tracey Daniels; Alistair J A Duff; Sarah Collins; Suja Chandran; Ursula Peaple; Matthew N Hurley; Keith Brownlee; Alan R Smyth
Journal:  Thorax       Date:  2017-08-04       Impact factor: 9.139

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  2 in total

Review 1.  A Systematic Review on KAP of Nebulization Therapy at Home.

Authors:  Shalini Sivadasan; Akshaya Krishnan; Sathish Venkatasamy Dhayalan; Rajasekaran Aiyalu
Journal:  J Pharm Technol       Date:  2021-07-11

Review 2.  Nebuliser hygiene in cystic fibrosis: evidence-based recommendations.

Authors:  Jane Bell; Lauren Alexander; Jane Carson; Amanda Crossan; John McCaughan; Hazel Mills; Damian O'Neill; John E Moore; B Cherie Millar
Journal:  Breathe (Sheff)       Date:  2020-06
  2 in total

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