| Literature DB >> 32029600 |
Kun Wu1, Shuansuo Wang1, Wenzhen Song1,2, Jianqing Zhang1,2, Yun Wang1,2, Qian Liu1, Jianping Yu1, Yafeng Ye1,3, Shan Li1,2, Jianfeng Chen1,2, Ying Zhao1,2, Jing Wang1,2, Xiaokang Wu1,2, Meiyue Wang4, Yijing Zhang4, Binmei Liu3, Yuejin Wu3, Nicholas P Harberd5, Xiangdong Fu6,2.
Abstract
Because environmentally degrading inorganic fertilizer use underlies current worldwide cereal yields, future agricultural sustainability demands enhanced nitrogen use efficiency. We found that genome-wide promotion of histone H3 lysine 27 trimethylation (H3K27me3) enables nitrogen-induced stimulation of rice tillering: APETALA2-domain transcription factor NGR5 (NITROGEN-MEDIATED TILLER GROWTH RESPONSE 5) facilitates nitrogen-dependent recruitment of polycomb repressive complex 2 to repress branching-inhibitory genes via H3K27me3 modification. NGR5 is a target of gibberellin receptor GIBBERELLIN INSENSITIVE DWARF1 (GID1)-promoted proteasomal destruction. DELLA proteins (characterized by the presence of a conserved aspartate-glutamate-leucine-leucine-alanine motif) competitively inhibit the GID1-NGR5 interaction and explain increased tillering of green revolution varieties. Increased NGR5 activity consequently uncouples tillering from nitrogen regulation, boosting rice yield at low nitrogen fertilization levels. NGR5 thus enables enhanced nitrogen use efficiency for improved future agricultural sustainability and food security.Entities:
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Year: 2020 PMID： 32029600 DOI： 10.1126/science.aaz2046
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728