Literature DB >> 32029408

The effect of Parkinson's disease on Chinese geriatric patients with intertrochanteric fracture: A propensity score-matched analysis.

Fei Xing1, Lang Li1, Wei Chen1, Zhou Xiang2.   

Abstract

BACKGROUND: Currently, few studies focus on the treatment of Parkinson's disease (PD) patients after a fracture. The effect of PD on geriatric patients with intertrochanteric fracture remains unclear. Therefore, we performed a study to focus on two questions as follow: (1) would PD increase the operation difficulty and perioperative complications in Chinese elderly patients with intertrochanteric fracture? (2) is there any difference between the clinical outcome of patients with and without PD? HYPOTHESIS: PD would increase perioperative complications and influence the postoperative rehabilitation in elderly patients with intertrochanteric fracture.
MATERIALS AND METHODS: There were 445 elderly intertrochanteric fracture patients treated with proximal femoral nail anti-rotation during January 2010 and December 2017. After propensity score matching, twenty-four geriatric intertrochanteric fracture patients with PD and forty-eight geriatric intertrochanteric fracture patients without PD were enrolled in this retrospective study. Intraoperative and postoperative comparison were conducted between patients with and without PD.
RESULTS: Compared with 63 months for geriatric intertrochanteric fracture patients without PD, patients with PD had a median survival time of 31 months. The Harris Hip Score and Barthel Index of patients with PD were significantly lower than that of patients without PD. In addition, the Depression subscale score of patients with PD were significantly higher that of patients without PD. DISCUSSION: The effect of PD on geriatric patients with intertrochanteric fracture is not the operation itself, but the postoperative rehabilitation. In addition, multi-disciplinary treatment, personal rehabilitation training, more intensive outpatient care, and meticulous nursing were recommended in treatment for elderly patients with intertrochanteric fracture and PD. LEVEL OF EVIDENCE: III, Cohort comparative study.
Copyright © 2020 Elsevier Masson SAS. All rights reserved.

Entities:  

Keywords:  Geriatric patients; Intertrochanteric fracture; Parkinson's disease; Propensity score-matched analysis

Mesh:

Year:  2020        PMID: 32029408     DOI: 10.1016/j.otsr.2019.11.022

Source DB:  PubMed          Journal:  Orthop Traumatol Surg Res        ISSN: 1877-0568            Impact factor:   2.256


  1 in total

1.  Efficacy and safety of tranexamic acid for patients with intertrochanteric fractures treated with intramedullary fixation: A systematic review and meta-analysis of current evidence in randomized controlled trials.

Authors:  Jiabao Jiang; Fei Xing; Man Zhe; Rong Luo; Jiawei Xu; Xin Duan; Zhou Xiang
Journal:  Front Pharmacol       Date:  2022-09-19       Impact factor: 5.988

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.