| Literature DB >> 32028988 |
Mayank N K Choudhary1, Ryan Z Friedman1, Julia T Wang1, Hyo Sik Jang1, Xiaoyu Zhuo1, Ting Wang2.
Abstract
Following publication of the original paper [1], an error was reported in the processing of Fig. 2. The correct Fig. 2 is supplied below and the original article [1] has been corrected. The publishers apologize for the error.Entities:
Year: 2020 PMID: 32028988 PMCID: PMC7006110 DOI: 10.1186/s13059-020-1944-4
Source DB: PubMed Journal: Genome Biol ISSN: 1474-7596 Impact factor: 13.583
Fig. 2Contribution of TEs to the conservation landscape of human and mouse loops. a Flowchart describing the methodology used to annotate loop orthology. b Venn diagram representing the various classes of chromatin loops based on their orthology and bar plots showing the contribution of REs to anchor CTCFs of each class of loops. c Age distribution and age of individual TEs that contribute loop anchor CTCF sites (black dots for orthologous loops; gold dots for non-orthologous loops) (left), total contribution to loop anchor CTCF sites (middle), distribution of orthologous and non-orthologous loops (right) derived from the top 13 TE subfamilies in mouse and d humans. Estimated primate/rodent divergence time (82 million years ago) is from Meredith et al. [47]. e Contact maps representing a conserved chromatin loop in a syntenic region between human and mouse. f A MER20 transposon insertion provides a redundant CTCF motif that helps in maintaining the conserved 3D structure in mouse via CTCF binding site turnover with remnants of the ancestral CTCF motif, well conserved in most non-rodent mammals (Additional file 1: Figure S2), still seen in the mouse genome