Literature DB >> 32028988

Publisher Correction: Co-opted transposons help perpetuate conserved higher-order chromosomal structures.

Mayank N K Choudhary1, Ryan Z Friedman1, Julia T Wang1, Hyo Sik Jang1, Xiaoyu Zhuo1, Ting Wang2.   

Abstract

Following publication of the original paper [1], an error was reported in the processing of Fig. 2. The correct Fig. 2 is supplied below and the original article [1] has been corrected. The publishers apologize for the error.

Entities:  

Year:  2020        PMID: 32028988      PMCID: PMC7006110          DOI: 10.1186/s13059-020-1944-4

Source DB:  PubMed          Journal:  Genome Biol        ISSN: 1474-7596            Impact factor:   13.583


Publisher Correction to: Genome Biol https://doi.org/10.1186/s13059-019-1916-8 Following publication of the original paper [1], an error was reported in the processing of Fig. 2. The correct Fig. 2 is supplied below and the original article [1] has been corrected. The publishers apologize for the error.
Fig. 2

Contribution of TEs to the conservation landscape of human and mouse loops. a Flowchart describing the methodology used to annotate loop orthology. b Venn diagram representing the various classes of chromatin loops based on their orthology and bar plots showing the contribution of REs to anchor CTCFs of each class of loops. c Age distribution and age of individual TEs that contribute loop anchor CTCF sites (black dots for orthologous loops; gold dots for non-orthologous loops) (left), total contribution to loop anchor CTCF sites (middle), distribution of orthologous and non-orthologous loops (right) derived from the top 13 TE subfamilies in mouse and d humans. Estimated primate/rodent divergence time (82 million years ago) is from Meredith et al. [47]. e Contact maps representing a conserved chromatin loop in a syntenic region between human and mouse. f A MER20 transposon insertion provides a redundant CTCF motif that helps in maintaining the conserved 3D structure in mouse via CTCF binding site turnover with remnants of the ancestral CTCF motif, well conserved in most non-rodent mammals (Additional file 1: Figure S2), still seen in the mouse genome

Contribution of TEs to the conservation landscape of human and mouse loops. a Flowchart describing the methodology used to annotate loop orthology. b Venn diagram representing the various classes of chromatin loops based on their orthology and bar plots showing the contribution of REs to anchor CTCFs of each class of loops. c Age distribution and age of individual TEs that contribute loop anchor CTCF sites (black dots for orthologous loops; gold dots for non-orthologous loops) (left), total contribution to loop anchor CTCF sites (middle), distribution of orthologous and non-orthologous loops (right) derived from the top 13 TE subfamilies in mouse and d humans. Estimated primate/rodent divergence time (82 million years ago) is from Meredith et al. [47]. e Contact maps representing a conserved chromatin loop in a syntenic region between human and mouse. f A MER20 transposon insertion provides a redundant CTCF motif that helps in maintaining the conserved 3D structure in mouse via CTCF binding site turnover with remnants of the ancestral CTCF motif, well conserved in most non-rodent mammals (Additional file 1: Figure S2), still seen in the mouse genome
  1 in total

1.  Co-opted transposons help perpetuate conserved higher-order chromosomal structures.

Authors:  Mayank Nk Choudhary; Ryan Z Friedman; Julia T Wang; Hyo Sik Jang; Xiaoyu Zhuo; Ting Wang
Journal:  Genome Biol       Date:  2020-01-24       Impact factor: 13.583

  1 in total
  2 in total

1.  In silico analysis of potential off-target sites to gene editing for Mucopolysaccharidosis type I using the CRISPR/Cas9 system: Implications for population-specific treatments.

Authors:  Paola Carneiro; Martiela Vaz de Freitas; Ursula Matte
Journal:  PLoS One       Date:  2022-01-24       Impact factor: 3.240

2.  Cas9 targeted enrichment of mobile elements using nanopore sequencing.

Authors:  Torrin L McDonald; Weichen Zhou; Christopher P Castro; Camille Mumm; Jessica A Switzenberg; Ryan E Mills; Alan P Boyle
Journal:  Nat Commun       Date:  2021-06-11       Impact factor: 14.919

  2 in total

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