Literature DB >> 32027561

Adipose Tissue-Derived Stem Cells: Immunomodulatory Effects and Therapeutic Potential.

Sara Al-Ghadban1, Bruce A Bunnell1,2.   

Abstract

Adipose-derived stem cells (ASCs) can self-renew and differentiate along multiple cell lineages. ASCs are also potently anti-inflammatory due to their inherent ability to regulate the immune system by secreting anti-inflammatory cytokines and growth factors that play a crucial role in the pathology of many diseases, including multiple sclerosis, diabetes mellitus, Crohn's, SLE, and graft-versus-host disease. The immunomodulatory effects and mechanisms of action of ASCs on pathological conditions are reviewed here.

Entities:  

Keywords:  adipose-derived stem cells; cytokines; immune cells; immunological disease; mechanisms of action; stromal vascular fraction

Year:  2020        PMID： 32027561     DOI： 10.1152/physiol.00021.2019

Source DB:  PubMed          Journal:  Physiology (Bethesda)        ISSN： 1548-9221


  16 in total

1.  Adipose-Derived Mesenchymal Stem Cells Reprogram M1 Macrophage Metabolism via PHD2/HIF-1α Pathway in Colitis Mice.

Authors:  Yin Yuan; Shuo Ni; Aoxiang Zhuge; Lanjuan Li; Bo Li
Journal:  Front Immunol       Date:  2022-06-10       Impact factor: 8.786

2.  Exosomes as Part of the Human Adipose-Derived Stem Cells Secretome- Opening New Perspectives for Cell-Free Regenerative Applications.

Authors:  Alexandra Dobranici; Ramona Tecucianu; Sorina Dinescu; Aida Selaru; Roxana Balahura; Simona Ignat; Marieta Costache
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

3.  Protective Effect of Membrane-Free Stem Cells against Lipopolysaccharide and Interferon-Gamma-Stimulated Inflammatory Responses in RAW 264.7 Macrophages.

Authors:  Mei Tong He; Hye Sook Park; Young Sil Kim; Ah Young Lee; Eun Ju Cho
Journal:  Int J Mol Sci       Date:  2021-06-27       Impact factor: 5.923

4.  Promotion of Hair Growth by Conditioned Medium from Extracellular Matrix/Stromal Vascular Fraction Gel in C57BL/6 Mice.

Authors:  Shune Xiao; Yurong Deng; Xiaojin Mo; Zhiyuan Liu; Dali Wang; Chengliang Deng; Zairong Wei
Journal:  Stem Cells Int       Date:  2020-06-13       Impact factor: 5.443

Review 5.  Circular RNAs in stem cells: from basic research to clinical implications.

Authors:  Hui-Juan Lu; Juan Li; Guodong Yang; Cun-Jian Yi; Daping Zhang; Fenggang Yu; Zhaowu Ma
Journal:  Biosci Rep       Date:  2022-01-28       Impact factor: 3.840

Review 6.  Adipose Stem Cells in Regenerative Medicine: Looking Forward.

Authors:  Sara Al-Ghadban; Maria Artiles; Bruce A Bunnell
Journal:  Front Bioeng Biotechnol       Date:  2022-01-13

Review 7.  Implantable Immunosuppressant Delivery to Prevent Rejection in Transplantation.

Authors:  Madonna Rica Anggelia; Ren-Wen Huang; Hui-Yun Cheng; Chih-Hung Lin; Cheng-Hung Lin
Journal:  Int J Mol Sci       Date:  2022-01-29       Impact factor: 5.923

Review 8.  The Crosstalk Between Adipose-Derived Stem or Stromal Cells (ASC) and Cancer Cells and ASC-Mediated Effects on Cancer Formation and Progression-ASCs: Safety Hazard or Harmless Source of Tropism?

Authors:  Vincent G J Guillaume; Tim Ruhl; Anja M Boos; Justus P Beier
Journal:  Stem Cells Transl Med       Date:  2022-04-29       Impact factor: 7.655

9.  3D Spheroids Derived from Human Lipedema ASCs Demonstrated Similar Adipogenic Differentiation Potential and ECM Remodeling to Non-Lipedema ASCs In Vitro.

Authors:  Sara Al-Ghadban; India A Pursell; Zaidmara T Diaz; Karen L Herbst; Bruce A Bunnell
Journal:  Int J Mol Sci       Date:  2020-11-07       Impact factor: 5.923

10.  Phenotypical Characterization and Neurogenic Differentiation of Rabbit Adipose Tissue-Derived Mesenchymal Stem Cells.

Authors:  Mária Tirpáková; Jaromír Vašíček; Andrea Svoradová; Andrej Baláži; Marián Tomka; Miroslav Bauer; Alexander Makarevich; Peter Chrenek
Journal:  Genes (Basel)       Date:  2021-03-17       Impact factor: 4.096
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