Antonio Barone1,2, Sibylle Chatelain3, Giacomo Derchi4, Federica Di Spirito5,6, Ranieri Martuscelli7, Massimo Porzio5,6, Ludovico Sbordone5,6. 1. Department of Surgical, Medical and Molecular Pathologies and of the Critical Area, School of Dental Medicine, University-Hospital of Pisa, Pisa, Italy. 2. Unit of Oral Surgery and Implantology, School of Dental Medicine, University-Hospitals of Geneva, Geneva, Switzerland. 3. Specialist in Oral Surgery and Implantology, Unit of Oral Surgery, Maxillofacial Surgery and Oral Medicine, University Hospitals of Vaud, Lausanne, Switzerland. 4. Unit of Oral Surgery and Stomatology, Department of Surgical, Medical and Molecular Pathologies and of the Critical Area, School of Dental Medicine, University-Hospital of Pisa, Pisa, Italy. 5. Department of Medicine, Surgery and Dentistry "Schola Medica Salernitana", School of Dentistry, University of Salerno, Salerno, Italy. 6. Complex Operating Unit of Odontostomatology, Head and Neck Clinical Department, Azienda Ospedaliero-Universitaria San Giovanni di Dio e Ruggi d'Aragona, Salerno, Italy. 7. Department of Neurosciences, Reproductive and Odontostomatological Sciences, Unit of Oro-Maxillofacial Oncology (UOC Maxillofacial Surgery) Clinical Department of Head and Neck (Chairman: Prof L.Califano), University of Naples "Federico II", Napoli, Italy.
Abstract
OBJECTIVE: The purpose of this retrospective study was to assess the influence of antibiotics on the development of alveolitis after tooth extractions. MATERIALS AND METHODS: The study population consisted of patients who had erupted tooth extractions in 3 centers. The patients' medical records were collected for several parameters. Moreover, use of antibiotics was evaluated. The primary outcome was the development of alveolitis during the postoperative period. The secondary outcome measure was the possible associations between alveolitis and other patients' characteristics. RESULTS: A total of 1579 patient charts were screened. The patients enrolled in the study were 418 (159 males and 259 females). Alveolitis was reported for 12 extraction sites (2.87%). Six were in the group of patients that received antibiotics (2.14% out of 280 patients treated with antibiotics), and six were in the group of patients that did not receive antibiotics (4.35% out of 138 patients not receiving antibiotics). None of patient-level parameters showed any significant association with the development of alveolitis. CONCLUSION: In conclusion, this study showed that the use of antibiotics after erupted tooth extractions is not useful in preventing alveolitis. Larger, prospective, and randomized studies are needed before incorporating these findings into the daily clinical practice.
OBJECTIVE: The purpose of this retrospective study was to assess the influence of antibiotics on the development of alveolitis after tooth extractions. MATERIALS AND METHODS: The study population consisted of patients who had erupted tooth extractions in 3 centers. The patients' medical records were collected for several parameters. Moreover, use of antibiotics was evaluated. The primary outcome was the development of alveolitis during the postoperative period. The secondary outcome measure was the possible associations between alveolitis and other patients' characteristics. RESULTS: A total of 1579 patient charts were screened. The patients enrolled in the study were 418 (159 males and 259 females). Alveolitis was reported for 12 extraction sites (2.87%). Six were in the group of patients that received antibiotics (2.14% out of 280 patients treated with antibiotics), and six were in the group of patients that did not receive antibiotics (4.35% out of 138 patients not receiving antibiotics). None of patient-level parameters showed any significant association with the development of alveolitis. CONCLUSION: In conclusion, this study showed that the use of antibiotics after erupted tooth extractions is not useful in preventing alveolitis. Larger, prospective, and randomized studies are needed before incorporating these findings into the daily clinical practice.
Authors: Rizwan Jouhar; Muhammad Adeel Ahmed; Hussain Abdulmuttalib Ali Almomen; Abdullah Amin Jawad BuHulayqah; Mohammed Yousef Ahmed Alkashi; Ahmed Adel A Al-Quraini; Naseer Ahmed Journal: Int J Environ Res Public Health Date: 2022-05-28 Impact factor: 4.614
Authors: Francesco D'Ambrosio; Federica Di Spirito; Alessandra Amato; Mario Caggiano; Roberto Lo Giudice; Stefano Martina Journal: Healthcare (Basel) Date: 2022-08-21