Literature DB >> 3202519

Epithelium-derived relaxing factor(s) and bronchial reactivity.

P M Vanhoutte1.   

Abstract

Damage to or dysfunction of respiratory epithelial cells may contribute to the etiology of bronchial hyperreactivity in asthma and airway infection. This brief overview summarizes the data, which suggest that release of relaxing factor(s) from epithelial cells may contribute to the regulation of bronchomotor tone. Reduced release of this epithelium-derived relaxing factor(s) may help to explain in part bronchial hyperreactivity secondary to epithelial damage.

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Year:  1988        PMID： 3202519     DOI： 10.1164/ajrccm/138.6_Pt_2.S24

Source DB:  PubMed          Journal:  Am Rev Respir Dis        ISSN： 0003-0805


  20 in total

1.  The site of disruption of the bronchial epithelium in asthmatic and non-asthmatic subjects.

Authors:  S Montefort; J A Roberts; R Beasley; S T Holgate; W R Roche
Journal:  Thorax       Date:  1992-07       Impact factor: 9.139

2.  Is the airway epithelium responsible for histamine metabolism in the trachea of guinea pigs?

Authors:  E G Lindström; R G Andersson; G Granérus; N Grundström
Journal:  Agents Actions       Date:  1991-05

3.  Pharmacological evaluation of a guinea-pig tracheal epithelium-derived inhibitory factor (EpDIF).

Authors:  L B Fernandes; R G Goldie
Journal:  Br J Pharmacol       Date:  1990-07       Impact factor: 8.739

4.  Response to oyster mushroom (Pleurotus ostreatus) extract by sensitized and nonsensitized guinea pig trachea.

Authors:  E N Schachter; E Zuskin; J Pucarin-Cvetkovic; A Chiarelli; S Goswami
Journal:  Lung       Date:  2011-06-12       Impact factor: 2.584

5.  Responsiveness of human isolated bronchial segments and its relationship to epithelial loss.

Authors:  T I Omari; M P Sparrow; H W Mitchell
Journal:  Br J Clin Pharmacol       Date:  1993-04       Impact factor: 4.335

6.  Effects of parainfluenza type 3 virus on guinea pig pulmonary alveolar macrophage functions in vitro.

Authors:  P A Henricks; B Van Esch; F Engels; F P Nijkamp
Journal:  Inflammation       Date:  1993-12       Impact factor: 4.092

7.  Nicotine-induced airway smooth muscle contraction: neural mechanisms involving the airway epithelium. Functional and histologic studies in vitro.

Authors:  H L Hahn; M Lang; S Bleicher; S Zwerenz; C Rausch
Journal:  Clin Investig       Date:  1992 Mar-Apr

8.  Attenuation of contractions to acetylcholine in canine bronchi by an endogenous nitric oxide-like substance.

Authors:  Y Gao; P M Vanhoutte
Journal:  Br J Pharmacol       Date:  1993-07       Impact factor: 8.739

9.  Cromakalim inhibits transmitter acetylcholine release in rat trachea by an action on epithelial cells and a diffusible factor.

Authors:  Ross Vlahos; Maurice E Fabiani; David F Story
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2003-09-18       Impact factor: 3.000

10.  Expression and generation of interleukin-8, IL-6 and granulocyte-macrophage colony-stimulating factor by bronchial epithelial cells and enhancement by IL-1 beta and tumour necrosis factor-alpha.

Authors:  O Cromwell; Q Hamid; C J Corrigan; J Barkans; Q Meng; P D Collins; A B Kay
Journal:  Immunology       Date:  1992-11       Impact factor: 7.397
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