Literature DB >> 32025115

Possible risk factors for acute and chronic deep periprosthetic joint infections in primary total knee arthroplasty. Do BMI, smoking, urinary tract infections, gender, and ASA classification have an impact?

E Schiffner1, D Latz1, A Karbowski2, J P Grassmann1, S Thelen1, S Gehrmann1, J Windolf1, J Schneppendahl1, P Jungbluth1.   

Abstract

PURPOSE: Aim of this retrospective study was to evaluate the impact of the patient related factors body mass index (BMI), urinary tract infection, current smoking, gender, and American Society of Anesthesiologists (ASA) classification on the incidence of acute and chronic deep periprosthetic joint infections (PJI) in total knee arthroplasty (TKA).
METHODS: All patients undergoing revision surgery for a deep PJI of primary TKA between July 2012 and December 2016 were included in this study. All relevant data was collected from the medical records. Acute deep PJI was defined when PJI was diagnosed within the first 6 weeks after primary TKA, chronic PJI was defined when patients demonstrated PJI later than 6 weeks after primary TKA.
RESULTS: A total of 57 patients was included in this study with 13 cases of acute PJI and 44 of chronic PJI. Overweight patients (BMI > 25 kg/m2) represent a significantly larger proportion in both PJI groups (p < 0.05). Current smokers had an significantly increased risk for acute and chronic PJI (p < 0.05). In the acute PJI group 46.2% patients had an postoperative urinary tract infection.
CONCLUSION: An elevated BMI (>25 kg/m2), current smoking and urinary tract infection are possible risk factors for acute and chronic deep PJI. After primary TKA screening for urinary tract infection is recommendable to prevent predominantly acute deep PJI.
© 2019 Professor P K Surendran Memorial Education Foundation. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Knee; Knee arthroplasty; Periprosthetic joint infection; Risk factors

Year:  2019        PMID: 32025115      PMCID: PMC6997665          DOI: 10.1016/j.jor.2019.11.035

Source DB:  PubMed          Journal:  J Orthop        ISSN: 0972-978X


  13 in total

Review 1.  Diagnosis and management of infection after total knee arthroplasty.

Authors:  Dean T Tsukayama; Victor M Goldberg; Richard Kyle
Journal:  J Bone Joint Surg Am       Date:  2003       Impact factor: 5.284

2.  The impact of patient and surgical factors on the rate of infection after primary total knee arthroplasty: an analysis of 64,566 joints from the New Zealand Joint Registry.

Authors:  E R Tayton; C Frampton; G J Hooper; S W Young
Journal:  Bone Joint J       Date:  2016-03       Impact factor: 5.082

3.  Definition of periprosthetic joint infection.

Authors:  Javad Parvizi; Thorsten Gehrke
Journal:  J Arthroplasty       Date:  2014-03-21       Impact factor: 4.757

Review 4.  Periprosthetic joint infection.

Authors:  Bhaveen H Kapadia; Richard A Berg; Jacqueline A Daley; Jan Fritz; Anil Bhave; Michael A Mont
Journal:  Lancet       Date:  2015-06-28       Impact factor: 79.321

5.  BMI is a key risk factor for early periprosthetic joint infection following total hip and knee arthroplasty.

Authors:  Patrick Jung; Arthur J Morris; Mark Zhu; Sally A Roberts; Chris Frampton; Simon W Young
Journal:  N Z Med J       Date:  2017-09-01

6.  Periprosthetic joint infection: the incidence, timing, and predisposing factors.

Authors:  Luis Pulido; Elie Ghanem; Ashish Joshi; James J Purtill; Javad Parvizi
Journal:  Clin Orthop Relat Res       Date:  2008-04-18       Impact factor: 4.176

Review 7.  The influence of body mass index on the outcomes of primary total knee arthroplasty.

Authors:  Hai-bo Si; Yi Zeng; Bin Shen; Jing Yang; Zong-ke Zhou; Peng-de Kang; Fu-xing Pei
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2014-09-13       Impact factor: 4.342

8.  Risk factors for deep infection after total knee arthroplasty: a meta-analysis.

Authors:  Jie Chen; Yunying Cui; Xin Li; Xiangwan Miao; Zhanpeng Wen; Yan Xue; Jing Tian
Journal:  Arch Orthop Trauma Surg       Date:  2013-04-05       Impact factor: 3.067

9.  Normal CRP and WBC values in total hip arthroplasty (THA) with signs of loosening. Do we need a joint aspiration?

Authors:  Erik Schiffner; David Latz; Simon Thelen; Jan P Grassmann; Alfred Karbowski; Joachim Windolf; Johannes Schneppendahl; Pascal Jungbluth
Journal:  J Clin Orthop Trauma       Date:  2018-09-26

Review 10.  Patient-Related Risk Factors for Periprosthetic Joint Infection after Total Joint Arthroplasty: A Systematic Review and Meta-Analysis.

Authors:  Setor K Kunutsor; Michael R Whitehouse; Ashley W Blom; Andrew D Beswick
Journal:  PLoS One       Date:  2016-03-03       Impact factor: 3.240

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  1 in total

1.  Similar infection rates in a new wound closure method following knee arthroplasty.

Authors:  Shuyang Liu; Samantha N Andrews; Landon H Morikawa; Maya Y Matsumoto; Kristin A Mathews; Cass K Nakasone
Journal:  J Orthop       Date:  2021-09-22
  1 in total

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