Nicholas Bene1, Xing Li2, Sumon Nandi3. 1. Tufts University School of Medicine, Boston, MA, USA. 2. Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. 3. The University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA.
Abstract
BACKGROUND: We sought to evaluate reoperation-free survival following I&D with modular component exchange of revision total joint arthroplasty (TJA). METHODS: Of revision TJAs from 2004 to 2012 (n = 4,166), 30 were I&D with modular component exchange after index revision for aseptic indications. Patients with (n = 12) and without (n = 18) reoperation for infection recurrence were analyzed. RESULTS: Reoperation-free survival (60% at mean 4.8 year follow-up) improved with increased duration of antibiotic therapy (p = 0.0185), with maximum benefit at 2 years. CONCLUSIONS: At least 2 years of antibiotic therapy should be administered after I&D with modular component exchange for acutely infected revision TJA. LEVEL OF EVIDENCE: Level III, retrospective comparative study.
BACKGROUND: We sought to evaluate reoperation-free survival following I&D with modular component exchange of revision total joint arthroplasty (TJA). METHODS: Of revision TJAs from 2004 to 2012 (n = 4,166), 30 were I&D with modular component exchange after index revision for aseptic indications. Patients with (n = 12) and without (n = 18) reoperation for infection recurrence were analyzed. RESULTS: Reoperation-free survival (60% at mean 4.8 year follow-up) improved with increased duration of antibiotic therapy (p = 0.0185), with maximum benefit at 2 years. CONCLUSIONS: At least 2 years of antibiotic therapy should be administered after I&D with modular component exchange for acutely infected revision TJA. LEVEL OF EVIDENCE: Level III, retrospective comparative study.
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