Literature DB >> 32022666

A solitary supraglottic neurofibroma presenting with obstructive sleep apnea in an adolescent.

Robert Hutnik1, Philip G Chen2, Melissa M Mortensen1.   

Abstract

None: Obstructive sleep apnea (OSA) is commonly encountered in the pediatric population and has a large differential diagnosis. As clinicians, we must determine who needs to undergo flexible laryngoscopy to rule out potential obstructing lesions causing OSA. This report presents a 16-year-old female who presented with snoring, "asthma," dysphagia, and OSA. Flexible laryngoscopy and computed tomography revealed a neurofibroma of the aryepiglottic fold without associated neurofibromatosis type 1. The patient underwent microlaryngoscopy and the lesion was excised using cold steel and a carbon dioxide laser. At 6 months' follow-up, the patient was breathing without difficulty and had no evidence of recurrence. Solitary laryngeal neurofibromas are extremely rare, and this is the first case of an adolescent with OSA caused by a solitary supraglottic neurofibroma. A supraglottic mass needs to be considered in the differential diagnosis of patients with OSA who fail conservative treatment, even a diagnosis as rare as a solitary laryngeal neurofibroma.
© 2020 American Academy of Sleep Medicine.

Entities:  

Keywords:  dyspnea; head and neck neoplasms; laryngeal neoplasms; neurofibroma; neurofibromatosis 1; obstructive; otorhinolaryngologic neoplasms; sleep apnea; snoring; supraglottis

Year:  2020        PMID: 32022666      PMCID: PMC7161452          DOI: 10.5664/jcsm.8290

Source DB:  PubMed          Journal:  J Clin Sleep Med        ISSN: 1550-9389            Impact factor:   4.062


  10 in total

1.  The biology and management of laryngeal neurofibroma.

Authors:  Reza Rahbar; Biana G Litrovnik; Sara O Vargas; Caroline D Robson; Roger C Nuss; Mira B Irons; Trevor J McGill; Gerald B Healy
Journal:  Arch Otolaryngol Head Neck Surg       Date:  2004-12

2.  MR in neurofibromatosis of the larynx.

Authors:  D S Martin; J Stith; E E Awwad; S Handler
Journal:  AJNR Am J Neuroradiol       Date:  1995-03       Impact factor: 3.825

3.  Neurofibroma of the larynx in neurofibromatosis: preoperative computed tomography and magnetic resonance imaging.

Authors:  M Nakahira; H Nakatani; S Sawada; S Matsumoto
Journal:  Arch Otolaryngol Head Neck Surg       Date:  2001-03

Review 4.  Guidelines for the diagnosis and management of individuals with neurofibromatosis 1.

Authors:  Rosalie E Ferner; Susan M Huson; Nick Thomas; Celia Moss; Harry Willshaw; D Gareth Evans; Meena Upadhyaya; Richard Towers; Michael Gleeson; Christine Steiger; Amanda Kirby
Journal:  J Med Genet       Date:  2006-11-14       Impact factor: 6.318

5.  Benign tumors of the larynx: a clinical study of 50 cases.

Authors:  Pawan Singhal; Amit Bhandari; Mahendra Chouhan; Man Prakash Sharma; Shivdutt Sharma
Journal:  Indian J Otolaryngol Head Neck Surg       Date:  2009-03-21

Review 6.  Pediatric Obstructive Sleep Apnea and Asthma: Clinical Implications.

Authors:  Michelle Trivedi; Mai ElMallah; Evan Bailey; Ted Kremer; Lawrence M Rhein
Journal:  Pediatr Ann       Date:  2017-09-01       Impact factor: 1.132

Review 7.  Diagnosis and Management of Solitary Laryngeal Neurofibromas.

Authors:  Lili Zhang; Juan Jiang; Chengping Hu; Huaping Yang; Pengbo Deng; Yuanyuan Li
Journal:  Am J Med Sci       Date:  2017-12-24       Impact factor: 2.378

8.  Neurofibromatosis of the larynx causing stridor and sleep apnea.

Authors:  Dhave Setabutr; Myrza R Perez; Mai Thy Truong; Craig W Senders; Brian K Rubinstein
Journal:  Am J Otolaryngol       Date:  2014-05-04       Impact factor: 1.808

9.  The Different Clinical Aspects of Pediatric Primary Airway Tumors in the Larynx, Trachea, and Bronchi.

Authors:  Hyun Ju Cho; Jisun Yoon; Eun Lee; Yoon Se Lee; Sang Yoon Kim; Jong Lyel Roh; Dong Kwan Kim; Se Hoon Choi; Seung Il Park; Yong Hee Kim; Kyung Nam Koh; Ho Joon Im; Jong Jin Seo; Soo Jong Hong; Jinho Yu
Journal:  J Korean Med Sci       Date:  2017-08       Impact factor: 2.153

10.  Massive Plexiform Neurofibroma of the Neck and Larynx.

Authors:  Mohammad Kamal Mobashir; Abd ElRaof Said Mohamed; Mohammad Waheed El-Anwar; Ahmad Ebrahim El Sayed; Mouhamad A Fouad
Journal:  Int Arch Otorhinolaryngol       Date:  2014-12-12
  10 in total

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