| Literature DB >> 32021860 |
Nicolas Kluger1, Philippe Guillem2,3, Minttu Kivivuori4, Kirsi Isoherranen1.
Abstract
Hidradenitis suppurativa (HS) is a chronic and recurrent inflammatory skin disorder affecting mainly the areas rich in apocrine sweat glands, such as the axillae, groins and buttocks. The role of mechanical pressure and friction due to clothing in the pathogenesis of HS lesions has been previously stressed. Here, we report 2 middle-aged men who presented with HS lesions/HS-like lesions on their amputation stump and review 2 additional cases from the literature. Management was challenging as 2 patients needed tumor necrosis αinhibitor while deroofing/surgery was the option for the 2 others. These cases highlight that mechanical pressure and friction are environmental factors that can play a role in the pathogenesis of HS lesions.Entities:
Keywords: Amputation; Friction; Hidradenitis suppurativa; Prosthesis; Stump
Year: 2019 PMID: 32021860 PMCID: PMC6995964 DOI: 10.1159/000503153
Source DB: PubMed Journal: Skin Appendage Disord ISSN: 2296-9160