Literature DB >> 32020627

Complications after thigh sarcoma resection.

Sarah M Elswick1, Daniel A Curiel1, Peter Wu1, Arya Akhavan2, Vanessa E Molinar1, Anita T Mohan1, Frank H Sim3, Jorys Martinez-Jorge1, Michel Saint-Cyr1.   

Abstract

BACKGROUND AND OBJECTIVES: Standard treatment for extremity sarcoma is limb-sparing surgery often with radiation, but complications occur frequently. We sought to determine factors predictive of wound complications after thigh sarcoma resection and reconstruction while analyzing trends over time.
METHODS: We reviewed all thigh defects requiring plastic surgeon reconstruction following sarcoma resection at our institution from 1997 to 2014. Patient demographics, comorbidities, operative characteristics, multi-modality therapies, and complications were analyzed. Wound complications were: infection, dehiscence, seroma, hematoma, or partial/total flap loss.
RESULTS: There were 159 thigh reconstructions followed for 30 months on average. Eighty-seven percent of patients underwent radiation and 42% had chemotherapy. Almost half (49.1%) had a complication. The most common wound complication was surgical site infection (23.3%) followed by dehiscence (19.5%), and seroma (10.7%). Less common were partial (2.5%) or total flap loss (0.6%). Reoperation was required in 21 patients (13.2%). Tobacco use, older patient age, cardiac disease, and higher body mass index were independently associated with wound complications. Complications trended towards decreasing over time, but this was not statistically significant.
CONCLUSIONS: Tobacco use, cardiac disease, and higher body mass index, but not the timing of reconstruction, appear to increase the risk of wound complications after thigh soft tissue sarcomas resection and plastic surgery reconstruction.
© 2020 Wiley Periodicals, Inc.

Entities:  

Keywords:  lower extremity; sarcoma; surgical flaps

Mesh:

Year:  2020        PMID: 32020627     DOI: 10.1002/jso.25830

Source DB:  PubMed          Journal:  J Surg Oncol        ISSN: 0022-4790            Impact factor:   3.454


  4 in total

1.  An extremely scarce incidence of primary Undifferentiated Pleomorphic Sarcoma of the Scalp of a 52-year-old female - A Case Report.

Authors:  Omar Al Laham; Gheed Abdul Khalek; Hazar Alboushi; Abd Al Hameed Al Mohammad; Mohamad Almaydaani; Alaa Alhanwt
Journal:  Int J Surg Case Rep       Date:  2022-09-19

2.  Surgical management of sarcoma in adolescent and young adult patients.

Authors:  Kazuhiko Hashimoto; Shunji Nishimura; Naohiro Oka; Masao Akagi
Journal:  BMC Res Notes       Date:  2020-05-26

3.  Novel Use of a Porcine Bladder Extracellular Matrix Scaffold to Treat Postoperative Seroma in a Total Knee Arthroplasty Patient.

Authors:  Patrick Bettiol; Cameron Cox; Chris Gerzina; Jordan Simpson; Brendan MacKay
Journal:  Arthroplast Today       Date:  2021-01-30

4.  Nomogram Predicting the Risk of Postoperative Major Wound Complication in Soft Tissue Sarcoma of the Trunk and Extremities after Preoperative Radiotherapy.

Authors:  Zhengxiao Ouyang; Sally Trent; Catherine McCarthy; Thomas Cosker; Duncan Whitwell; Harriet Branford-White; Christopher Leonard Maxime Hardwicke Gibbons
Journal:  Cancers (Basel)       Date:  2022-08-24       Impact factor: 6.575

  4 in total

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