Literature DB >> 320169

Norvaline accumulation by regulatory mutants of Serratia marcescens.

M Kisumi, M Sugiura, T Takagi, I Chibata.   

Abstract

A gene coding for desensitized L-threonine dehydratase was transduced with phage PS20 into a leucine accumulator of Serratia marcescens Sr41. The transductant converted L-threonine to alpha-ketobutyrate, a precursor of both norvaline and isoleucine. An isoleucine-valine auxotroph of the transductant accumulated large amount of norvaline from L-threonine as well as from D-threonine.

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Year:  1977        PMID: 320169     DOI: 10.7164/antibiotics.30.111

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  6 in total

1.  L-Histidine production by histidase-less regulatory mutants of Serratia marcescens constructed by transduction.

Authors:  M Kisumi; N Nakanishi; T Takagi; I Chibata
Journal:  Appl Environ Microbiol       Date:  1977-11       Impact factor: 4.792

2.  Norleucine accumulation by a norleucine-resistant mutant of Serratia marcescens.

Authors:  M Kisumi; M Sugiura; I Chibata
Journal:  Appl Environ Microbiol       Date:  1977-08       Impact factor: 4.792

3.  Transductional construction of a threonine-producing strain of Serratia marcescens.

Authors:  S Komatsubara; M Kisumi; I Chibata
Journal:  Appl Environ Microbiol       Date:  1979-12       Impact factor: 4.792

Review 4.  Role of the metabolism of branched-chain amino acids in the development of Alzheimer's disease and other metabolic disorders.

Authors:  Baruh Polis; Abraham O Samson
Journal:  Neural Regen Res       Date:  2020-08       Impact factor: 5.135

5.  Norvaline is accumulated after a down-shift of oxygen in Escherichia coli W3110.

Authors:  Jaakko Soini; Christina Falschlehner; Christina Liedert; Jörg Bernhardt; Jussi Vuoristo; Peter Neubauer
Journal:  Microb Cell Fact       Date:  2008-10-21       Impact factor: 5.328

6.  Norvaline Restores the BBB Integrity in a Mouse Model of Alzheimer's Disease.

Authors:  Baruh Polis; Vyacheslav Gurevich; Michael Assa; Abraham O Samson
Journal:  Int J Mol Sci       Date:  2019-09-18       Impact factor: 5.923

  6 in total

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