Literature DB >> 32016626

The CKiD study: overview and summary of findings related to kidney disease progression.

Meredith A Atkinson1, Derek K Ng2, Bradley A Warady3, Susan L Furth4, Joseph T Flynn5.   

Abstract

The Chronic Kidney Disease in Children (CKiD) cohort study is a North American (USA and Canada) multicenter, prospective study of children with chronic kidney disease (CKD). The original aims of the study were (1) to identify novel risk factors for CKD progression; (2) to measure the impact of kidney function decline on growth, cognition, and behavior; and (3) to characterize the evolution of cardiovascular disease risk factors. CKiD has developed into a national and international resource for the investigation of a variety of factors related to CKD in children. This review highlights notable findings in the area of CKD progression and outlines ongoing opportunities to enhance understanding of CKD progression in children. CKiD's contributions to the clinical care of children with CKD include updated and more accurate glomerular filtration rate estimating equations for children and young adults, and resources designed to help estimate the CKD progression timeline. In addition, results from CKiD have strengthened the evidence that treatment of hypertension and proteinuria should continue as a primary strategy for slowing the rate of disease progression in children.

Entities:  

Keywords:  CKD; Children; Cohort; Hypertension; Proteinuria; Risk factors

Mesh：

Year:  2020        PMID： 32016626      PMCID： PMC7396280          DOI： 10.1007/s00467-019-04458-6

Source DB:  PubMed          Journal:  Pediatr Nephrol        ISSN： 0931-041X            Impact factor:   3.714


  48 in total

1.  APOL1 risk variants, race, and progression of chronic kidney disease.

Authors:  Afshin Parsa; W H Linda Kao; Dawei Xie; Brad C Astor; Man Li; Chi-yuan Hsu; Harold I Feldman; Rulan S Parekh; John W Kusek; Tom H Greene; Jeffrey C Fink; Amanda H Anderson; Michael J Choi; Jackson T Wright; James P Lash; Barry I Freedman; Akinlolu Ojo; Cheryl A Winkler; Dominic S Raj; Jeffrey B Kopp; Jiang He; Nancy G Jensvold; Kaixiang Tao; Michael S Lipkowitz; Lawrence J Appel
Journal:  N Engl J Med       Date:  2013-11-09       Impact factor: 91.245

2.  Parental health literacy and progression of chronic kidney disease in children.

Authors:  Ana C Ricardo; Lynn N Pereira; Aisha Betoko; Vivien Goh; Amatur Amarah; Bradley A Warady; Marva Moxey-Mims; Susan Furth; James P Lash
Journal:  Pediatr Nephrol       Date:  2018-06-14       Impact factor: 3.714

3.  Predictors of Rapid Progression of Glomerular and Nonglomerular Kidney Disease in Children and Adolescents: The Chronic Kidney Disease in Children (CKiD) Cohort.

Authors:  Bradley A Warady; Alison G Abraham; George J Schwartz; Craig S Wong; Alvaro Muñoz; Aisha Betoko; Mark Mitsnefes; Frederick Kaskel; Larry A Greenbaum; Robert H Mak; Joseph Flynn; Marva M Moxey-Mims; Susan Furth
Journal:  Am J Kidney Dis       Date:  2015-03-19       Impact factor: 8.860

4.  Fibroblast Growth Factor 23 and Risk of CKD Progression in Children.

Authors:  Anthony A Portale; Myles S Wolf; Shari Messinger; Farzana Perwad; Harald Jüppner; Bradley A Warady; Susan L Furth; Isidro B Salusky
Journal:  Clin J Am Soc Nephrol       Date:  2016-08-25       Impact factor: 8.237

Review 5.  Health literacy and child health outcomes: a systematic review of the literature.

Authors:  Darren A DeWalt; Ashley Hink
Journal:  Pediatrics       Date:  2009-11       Impact factor: 7.124

6.  Prevalence and correlates of 25-hydroxyvitamin D deficiency in the Chronic Kidney Disease in Children (CKiD) cohort.

Authors:  Juhi Kumar; Kelly McDermott; Alison G Abraham; Lisa Aronson Friedman; Valerie L Johnson; Frederick J Kaskel; Susan L Furth; Bradley A Warady; Anthony A Portale; Michal L Melamed
Journal:  Pediatr Nephrol       Date:  2015-08-26       Impact factor: 3.714

7.  Design and methods of the Chronic Kidney Disease in Children (CKiD) prospective cohort study.

Authors:  Susan L Furth; Stephen R Cole; Marva Moxey-Mims; Frederick Kaskel; Robert Mak; George Schwartz; Craig Wong; Alvaro Muñoz; Bradley A Warady
Journal:  Clin J Am Soc Nephrol       Date:  2006-07-19       Impact factor: 8.237

8.  Kidney Disease Progression in Autosomal Recessive Polycystic Kidney Disease.

Authors:  Katherine M Dell; Matthew Matheson; Erum A Hartung; Bradley A Warady; Susan L Furth
Journal:  J Pediatr       Date:  2016-01-28       Impact factor: 4.406

9.  APOL1-associated glomerular disease among African-American children: a collaboration of the Chronic Kidney Disease in Children (CKiD) and Nephrotic Syndrome Study Network (NEPTUNE) cohorts.

Authors:  Derek K Ng; Catherine C Robertson; Robert P Woroniecki; Sophie Limou; Christopher E Gillies; Kimberly J Reidy; Cheryl A Winkler; Sangeeta Hingorani; Keisha L Gibson; Rebecca Hjorten; Christine B Sethna; Jeffrey B Kopp; Marva Moxey-Mims; Susan L Furth; Bradley A Warady; Matthias Kretzler; John R Sedor; Frederick J Kaskel; Matthew G Sampson
Journal:  Nephrol Dial Transplant       Date:  2017-06-01       Impact factor: 5.992

10.  Blood lead level and measured glomerular filtration rate in children with chronic kidney disease.

Authors:  Jeffrey J Fadrowski; Alison G Abraham; Ana Navas-Acien; Eliseo Guallar; Virginia M Weaver; Susan L Furth
Journal:  Environ Health Perspect       Date:  2013-05-21       Impact factor: 9.031
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  8 in total

1.  Nocturnal Dipping and Left Ventricular Mass Index in the Chronic Kidney Disease in Children Cohort.

Authors:  Christine Y Bakhoum; Ronit Katz; Joshua A Samuels; Tala Al-Rousan; Susan L Furth; Joachim H Ix; Pranav S Garimella
Journal:  Clin J Am Soc Nephrol       Date:  2021-11-12       Impact factor: 8.237

2.  Mortality Risk Factors among Infants Receiving Dialysis in the Neonatal Intensive Care Unit.

Authors:  Keia R Sanderson; Bradley Warady; William Carey; Veeral Tolia; Marcella H Boynton; Daniel K Benjamin; Wesley Jackson; Matthew Laughon; Reese H Clark; Rachel G Greenberg
Journal:  J Pediatr       Date:  2021-11-16       Impact factor: 4.406

3.  Urine Biomarkers of Kidney Tubule Health, Injury, and Inflammation are Associated with Progression of CKD in Children.

Authors:  Jason H Greenberg; Alison G Abraham; Yunwen Xu; Jeffrey R Schelling; Harold I Feldman; Venkata S Sabbisetti; Joachim H Ix; Manasi P Jogalekar; Steven Coca; Sushrut S Waikar; Michael G Shlipak; Bradley A Warady; Ramachandran S Vasan; Paul L Kimmel; Joseph V Bonventre; Michelle Denburg; Chirag R Parikh; Susan Furth
Journal:  J Am Soc Nephrol       Date:  2021-09-20       Impact factor: 14.978

4.  The Relationship Between Neighborhood Disadvantage and Kidney Disease Progression in the Chronic Kidney Disease in Children (CKiD) Cohort.

Authors:  Sara A Boynton; Matthew B Matheson; Derek K Ng; Guillermo Hidalgo; Bradley A Warady; Susan L Furth; Meredith A Atkinson
Journal:  Am J Kidney Dis       Date:  2022-01-25       Impact factor: 11.072

Review 5.  Kidney Disease Progression in Children and Young Adults With Pediatric CKD: Epidemiologic Perspectives and Clinical Applications.

Authors:  Derek K Ng; Christopher B Pierce
Journal:  Semin Nephrol       Date:  2021-09       Impact factor: 4.472

6.  Organophosphate pesticides and progression of chronic kidney disease among children: A prospective cohort study.

Authors:  Melanie H Jacobson; Yinxiang Wu; Mengling Liu; Kurunthachalam Kannan; Adela Jing Li; Morgan Robinson; Bradley A Warady; Susan Furth; Howard Trachtman; Leonardo Trasande
Journal:  Environ Int       Date:  2021-05-02       Impact factor: 13.352

7.  Epidemiology of Chronic Kidney Disease in Children: A Report from Lithuania.

Authors:  Jūratė Masalskienė; Šarūnas Rudaitis; Renata Vitkevič; Rimantė Čerkauskienė; Diana Dobilienė; Augustina Jankauskienė
Journal:  Medicina (Kaunas)       Date:  2021-01-26       Impact factor: 2.430

Review 8.  Addressing the Ethical Challenges of Providing Kidney Failure Care for Children: A Global Stance.

Authors:  Priya Pais; Aaron Wightman
Journal:  Front Pediatr       Date:  2022-03-11       Impact factor: 3.418
  8 in total

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