| Literature DB >> 32013614 |
Babak Roshanravan1, Saeed Samarghandian2, Milad Ashrafizadeh3, Alireza Amirabadizadeh4, Farhad Saeedi1, Tahereh Farkhondeh4.
Abstract
The present systematic and meta-analysis study was designed to show the protective impact of saffron and crocin supplementation on hyperlipidaemia and hyperglycaemia in randomised and clinical trials (RCTs). A pooled analysis using a model for random-effects showed that HDL-C levels were 0.21 fold higher in the saffron and 0.01 fold higher in the crocin group than placebo. LDL-C levels in the saffron group reduced by 0.51 and 0.04 fold in the crocin group versus the placebo. Moreover, TC levels in the saffron group were 0.19 lower and 0.11 fold lower in crocin group than in the placebo group. TG level in saffron group was 0.04 lower and 0.02 fold lower in crocin than the control group. The blood glucose levels did not significantly differ from the control group. This study suggests that saffron and crocin may modulate the serum lipid profile in patient with metabolic disorders.Entities:
Keywords: HDL; LDL; Saffron; cholesterol; crocin; glucose; triglyceride
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Year: 2020 PMID： 32013614 DOI： 10.1080/13813455.2020.1716020
Source DB: PubMed Journal: Arch Physiol Biochem ISSN： 1381-3455 Impact factor: 4.076