| Literature DB >> 32011898 |
Shihan Liu1, Tao Zhang2, Lei Zhu1, Fenru Liu1, Ruopeng Bai1, Yu Lan1,2.
Abstract
A three-layer chirality relay model is proposed for Rh(I)-mediated enantioselective siletane activation. A chiral ligand in the back layer controls the position of the alkyne-coordinated metal center in the middle layer, which then provides a chiral environment for the incoming substrate at the front layer. A two-dimensional contour map analysis further clarified this model.Entities:
Year: 2020 PMID： 32011898 DOI： 10.1021/acs.orglett.9b04636
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005