Literature DB >> 3200934

Cytotoxic and antitumor activities of Rabdosia diterpenoids.

T Fujita, Y Takeda, H D Sun, Y Minami, T Marunaka, S Takeda, Y Yamada, T Togo.   

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Year:  1988        PMID： 3200934     DOI： 10.1055/s-2006-962485

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


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  6 in total

1.  Effective compounds screening from Rabdosia serra (Maxim) Hara against HBV and tumor in vitro.

Authors:  Cheng Chen; Yang Chen; Hongyuan Zhu; Yiyun Xiao; Xiuzhen Zhang; Jingfeng Zhao; Yuxiang Chen
Journal:  Int J Clin Exp Med       Date:  2014-02-15

2.  Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo.

Authors:  Guang-Biao Zhou; Hui Kang; Lan Wang; Li Gao; Ping Liu; Jun Xie; Feng-Xiang Zhang; Xiang-Qin Weng; Zhi-Xiang Shen; Jue Chen; Long-Jun Gu; Ming Yan; Dong-Er Zhang; Sai-Juan Chen; Zhen-Yi Wang; Zhu Chen
Journal:  Blood       Date:  2006-12-29       Impact factor: 22.113

3.  Oridonin in combination with imatinib exerts synergetic anti-leukemia effect in Ph+ acute lymphoblastic leukemia cells in vitro by inhibiting activation of LYN/mTOR signaling pathway.

Authors:  Yong Guo; Qingqing Shan; Yuping Gong; Juan Lin; Xi Yang; Ruiqing Zhou
Journal:  Cancer Biol Ther       Date:  2012-08-16       Impact factor: 4.742

4.  Oridonin inhibits aberrant AKT activation in breast cancer.

Authors:  Bowen Sun; Geng Wang; Huidong Liu; Pian Liu; Waleed O Twal; Hiuwing Cheung; Steven L Carroll; Stephen P Ethier; Emily E Mevers; Jon Clardy; Thomas Roberts; Changbin Chen; Qian Li; Lanfeng Wang; Meixiang Yang; Jean J Zhao; Qi Wang
Journal:  Oncotarget       Date:  2018-02-01

5.  Inhibition of caspase-9 by oridonin, a diterpenoid isolated from Rabdosia rubescens, augments apoptosis in human laryngeal cancer cells.

Authors:  Ning Kang; Shi-Jie Cao; Yan Zhou; Hao He; Shin-Ichi Tashiro; Satoshi Onodera; Feng Qiu; Takashi Ikejima
Journal:  Int J Oncol       Date:  2015-09-28       Impact factor: 5.650

6.  Oridonin Enhances Radiation-Induced Cell Death by Promoting DNA Damage in Non-Small Cell Lung Cancer Cells.

Authors:  Hyejin Park; Ye Ji Jeong; Na-Kyung Han; Joong Sun Kim; Hae-June Lee
Journal:  Int J Mol Sci       Date:  2018-08-13       Impact factor: 5.923
  6 in total

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