| Literature DB >> 32008688 |
Isabella Pacchiarotti1, Giorgio D Kotzalidis2, Andrea Murru1, Lorenzo Mazzarini2, Chiara Rapinesi2, Marc Valentí1, Gerard Anmella1, Susana Gomes-da-Costa1, Anna Gimenez1, Cristian Llach1, Giulio Perugi3, Eduard Vieta4, Norma Verdolini1.
Abstract
The Diagnostic and Statistical Manual of Mental Disorders Fifth Edition introduced the specifier "with mixed features" including 3 or more nonoverlapping typical manic symptoms during a major depressive episode in bipolar disorder type I or II or unipolar major depressive disorder. Excluding overlapping excitatory symptoms, which are frequently observed in mixed depression, leaves many patients with mixed depression undiagnosed. As a consequence, alternative diagnostic criteria have been proposed, claiming for the inclusion in the rubric of mixed features the following symptoms: psychomotor agitation, mood lability, and aggressiveness. A deeper diagnostic reconsideration of mixed features in depression should be provided by the new nosologic classification systems.Entities:
Keywords: Bipolar disorder; DSM-5; Major depressive disorder; Mixed features specifier; Nonoverlapping symptoms; Overlapping symptoms
Mesh：
Year: 2019 PMID： 32008688 DOI： 10.1016/j.psc.2019.10.006
Source DB: PubMed Journal: Psychiatr Clin North Am ISSN： 0193-953X