Literature DB >> 32003658

Radiolabeled Peptides for SPECT and PET Imaging in the Detection of Breast Cancer: Preclinical and Clinical Perspectives.

Hao Fu1, Bulin Du2, Zijun Chen1, Yesen Li3.   

Abstract

Breast cancer is the most common cancer in women worldwide. Due to the heterogeneous nature of breast cancer, the optimal treatment and expected response for each patient may not necessarily be universal. Molecular imaging techniques could play an important role in the early detection and targeted therapy evaluation of breast cancer. This review focuses on the development of peptides labeled with SPECT and PET radionuclides for breast cancer imaging. We summarized the current status of radiolabeled peptides for different receptors in breast cancer. The characteristics of radionuclides and major techniques for peptide labeling are also briefly discussed. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

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Keywords:  Breast cancer; PET Imaging; Radiolabeled Peptides; SPECT Imaging; Single-zzm321990Photon Emission Tomography (SPECT); heterogeneous cancer

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Year:  2020        PMID: 32003658     DOI: 10.2174/0929867327666200128110827

Source DB:  PubMed          Journal:  Curr Med Chem        ISSN: 0929-8673            Impact factor:   4.530


  1 in total

1.  Phenylboronic acid conjugated multifunctional nanogels with 131I-labeling for targeted SPECT imaging and radiotherapy of breast adenocarcinoma.

Authors:  Lingdan Kong; Jingyi Zhu; Hongxing Su; Lingzhou Zhao; Yi Lu; Meilin Zhu; Wenjie Sun
Journal:  Front Bioeng Biotechnol       Date:  2022-07-22
  1 in total

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