Literature DB >> 32001237

Natural products target the hallmarks of chronic diseases.

Marc Diederich1.   

Abstract

Natural compounds are known to display therapeutic potential against a variety of chronic conditions, including cancer and inflammation. The efficacy of these natural substances can be associated with numerous molecular scaffolds present in extracts of living organisms, both terrestrial and marine. Recently, investigators have identified the ability of natural compounds to trigger immunogenic cell death and subsequent activation of the adaptive immune system. Such findings indicate that the full therapeutic potential of natural products has yet to be defined, and further investigations on such agents will continue to yield novel drug candidates.
Copyright © 2020 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Antiaging; Natural compounds; Noncommunicable disease; Nuclear factor erythroid 2-related factor 2; Polyphenol; Polyunsaturated fatty acid

Year:  2020        PMID: 32001237     DOI: 10.1016/j.bcp.2020.113828

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN: 0006-2952            Impact factor:   5.858


  3 in total

Review 1.  Can Natural Products be Used to Overcome the Limitations of Colorectal Cancer Immunotherapy?

Authors:  Jiahuan Dong; Yufan Qian; Guangtao Zhang; Lu Lu; Shengan Zhang; Guang Ji; Aiguang Zhao; Hanchen Xu
Journal:  Front Oncol       Date:  2022-05-04       Impact factor: 5.738

2.  Anti-Inflammatory and Immunomodulatory Effects of the Grifola frondosa Natural Compound o-Orsellinaldehyde on LPS-Challenged Murine Primary Glial Cells. Roles of NF-κβ and MAPK.

Authors:  Sarah Tomas-Hernandez; Jordi Blanco; Santiago Garcia-Vallvé; Gerard Pujadas; María José Ojeda-Montes; Aleix Gimeno; Lluís Arola; Luisa Minghetti; Raúl Beltrán-Debón; Miquel Mulero
Journal:  Pharmaceutics       Date:  2021-05-28       Impact factor: 6.321

3.  Effects of supplementation with kombucha and green banana flour on Wistar rats fed with a cafeteria diet.

Authors:  Marianela Andrea Díaz Urrutia; Amanda Gemelli Ramos; Rafaela Beatriz Menegusso; Rafael Dewes Lenz; Mateus Gemelli Ramos; Adriana Gadioli Tarone; Cinthia Baú Betim Cazarin; Solange Maria Cottica; Sóstenez Alexandre Vessaro da Silva; Daniela Miotto Bernardi
Journal:  Heliyon       Date:  2021-05-18
  3 in total

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