RATIONALE: Uptake of the COPD Assessment Test (CATTM) is not yet widespread in patients with chronic obstructive pulmonary disease (COPD) within U.S. primary care and its alignment with other assessments has not been evaluated in U.S. clinical practice. OBJECTIVES: To assess the alignment of the CAT with other standard measures of COPD severity and its usability in a U.S. primary care population. METHODS: This was a multicenter, prospective, observational, longitudinal study of patients with COPD and their primary care physicians. Patients with spirometry-confirmed airflow restriction completed a daily electronic diary (eDiary) over 12 weeks; surveys were also administered at baseline and at 6- and 12-week follow-up. MEASUREMENTS AND MAIN RESULTS: In the study population (n=178), statistically significant differences (P<0.05) were found across 4 CAT impact score groups where at all time points patients in the Low Impact CAT score group had superior lung function and physical/mental health status than patients in the Medium, High, and Very High Impact groups. Numerical, though lesser, differences were also found across these latter 3 groups. Furthermore, the average total EXAcerbations of COPD Tool (EXACT®) score was significantly worse in patients in the highest CAT score group over the first 7 days. CONCLUSIONS: COPD severity; respiratory symptoms; frequency, severity, and duration of pulmonary exacerbations; and overall physical and mental health status are linked concurrently and prospectively to CAT impact score categories. The stratification of patients according to CAT impact scores, and application of clinical and functional health status information to these categories, enhances the usability of the CAT in practice settings for COPD management. JCOPDF
RATIONALE: Uptake of the COPD Assessment Test (CATTM) is not yet widespread in patients with chronic obstructive pulmonary disease (COPD) within U.S. primary care and its alignment with other assessments has not been evaluated in U.S. clinical practice. OBJECTIVES: To assess the alignment of the CAT with other standard measures of COPD severity and its usability in a U.S. primary care population. METHODS: This was a multicenter, prospective, observational, longitudinal study of patients with COPD and their primary care physicians. Patients with spirometry-confirmed airflow restriction completed a daily electronic diary (eDiary) over 12 weeks; surveys were also administered at baseline and at 6- and 12-week follow-up. MEASUREMENTS AND MAIN RESULTS: In the study population (n=178), statistically significant differences (P<0.05) were found across 4 CAT impact score groups where at all time points patients in the Low Impact CAT score group had superior lung function and physical/mental health status than patients in the Medium, High, and Very High Impact groups. Numerical, though lesser, differences were also found across these latter 3 groups. Furthermore, the average total EXAcerbations of COPD Tool (EXACT®) score was significantly worse in patients in the highest CAT score group over the first 7 days. CONCLUSIONS: COPD severity; respiratory symptoms; frequency, severity, and duration of pulmonary exacerbations; and overall physical and mental health status are linked concurrently and prospectively to CAT impact score categories. The stratification of patients according to CAT impact scores, and application of clinical and functional health status information to these categories, enhances the usability of the CAT in practice settings for COPD management. JCOPDF
Authors: Alex J Mackay; Konstantinos Kostikas; Lindsey Murray; Fernando J Martinez; Marc Miravitlles; Gavin Donaldson; Donald Banerji; Francesco Patalano; Jadwiga A Wedzicha Journal: Am J Respir Crit Care Med Date: 2018-09-15 Impact factor: 21.405
Authors: Nicola A Hanania; David M Mannino; Barbara P Yawn; Douglas W Mapel; Fernando J Martinez; James F Donohue; Mark Kosinski; Regina Rendas-Baum; Matthew Mintz; Steven Samuels; Priti Jhingran; Anand A Dalal Journal: Respir Med Date: 2010-03-11 Impact factor: 3.415
Authors: Alex J Mackay; Gavin C Donaldson; Anant R C Patel; Paul W Jones; John R Hurst; Jadwiga A Wedzicha Journal: Am J Respir Crit Care Med Date: 2012-01-26 Impact factor: 21.405
Authors: Barbara P Yawn; Douglas W Mapel; David M Mannino; Fernando J Martinez; James F Donohue; Nicola A Hanania; Mark Kosinski; Regina Rendas-Baum; Matthew Mintz; Steven Samuels; Anand A Dalal Journal: Int J Chron Obstruct Pulmon Dis Date: 2010-02-18
Authors: James W Dodd; Lauren Hogg; Jane Nolan; Helen Jefford; Amy Grant; Victoria M Lord; Christine Falzon; Rachel Garrod; Cassandra Lee; Michael I Polkey; Paul W Jones; William D-C Man; Nicholas S Hopkinson Journal: Thorax Date: 2011-03-12 Impact factor: 9.139
Authors: Kevin Gruffydd-Jones; Helen C Marsden; Steve Holmes; Peter Kardos; Roger Escamilla; Roberto Dal Negro; June Roberts; Gilbert Nadeau; Mathieu Vasselle; David A Leather; Paul Jones Journal: Prim Care Respir J Date: 2013-03