Literature DB >> 31999633

Management of a difficult infectional disease: Descending necrotizing mediastinitis.

Fazlı Yanık1, Yekta Altemur Karamustafaoğlu2, Yener Yoruk3.   

Abstract

INTRODUCTION: Descending Necrotizing Mediastinitis (DNM) is the fatal form of mediastinitis and mostly develops as a complication of peritonsillar abscesses or dental-odontogenic infections. The aim of this study is to evaluate clinical and surgical feature of the patients with DNM who were managed in our clinic.
METHODOLOGY: We retrospectively evaluated 13 consecutive patients with the diagnosis of DNM between February 2005 and February 2018. All of them had the typical physical appearance, history and radiological findings.
RESULTS: Ten (77%) patients were male, 3 (23%) patients were female with a median age of 48.2 (18-76 years). All patients underwent Cervico-Mediastinal Drainage (CMD) with debridement of the necrotic and infected tissues. Other supplimantary surgical procedures were tube thoracostomy (n = 8), VATS mediastinal drainage (n = 4), tracheostomy (n = 2) and thoracatomy (n = 1). The median time to diagnosis of DNM, tube drainage (inserted after CMD) removal time, tube thoracostomy removal time, lenght of hospital stay were 1.8 (range 1-4) days, 13.6 (range 10-20), 12.6 days (range 10-27) and 21.5 days (range 15-30), respectively. Appropriate and potent antibiotics were used according to the fever-CRP response with the consultation on infectious disease specialist. Two patients were lost due to fulminant sepsis (n = 1) and massive cervical haemorrhage (n = 1). Overall mortality rate was 15%. Complications were recorded in 6 patients (46%).
CONCLUSIONS: The critical point in the management of DNM is the correct diagnosis, rapid surgical intervention with antibiotherapy and close follow-up for possible complications. We concluded that the combination of minimally invasive management as VATS-tube thoracostomy with CMD is the most appropriate surgical interventions. Copyright (c) 2018 Fazlı Yanık, Yekta Altemur Karamustafaoğlu, Yener Yoruk.

Entities:  

Keywords:  fatal; infection; mediastinitis; mediastinum

Mesh:

Substances:

Year:  2018        PMID: 31999633     DOI: 10.3855/jidc.10482

Source DB:  PubMed          Journal:  J Infect Dev Ctries        ISSN: 1972-2680            Impact factor:   0.968


  3 in total

1.  Multidisciplinary Approach in the Treatment of Descending Necrotizing Mediastinitis: Twenty-Year Single-Center Experience.

Authors:  Angela De Palma; Mirko Girolamo Cantatore; Francesco Di Gennaro; Francesca Signore; Teodora Panza; Debora Brascia; Giulia De Iaco; Doroty Sampietro; Rosatea Quercia; Marcella Genualdo; Ondina Pizzuto; Giuseppe Garofalo; Fabio Signorile; Davide Fiore Bavaro; Gaetano Brindicci; Nicolò De Gennaro; Annalisa Saracino; Nicola Antonio Adolfo Quaranta; Gianfranco Favia; Giuseppe Marulli
Journal:  Antibiotics (Basel)       Date:  2022-05-16

2.  Acute Mediastinitis - Outcomes and Prognostic Factors of Surgical Therapy (A Single-Center Experience).

Authors:  Josef Vodička; Jan Geiger; Alexandra Židková; Pavel Andrle; Hynek Mírka; Martin Svatonˇ; Tomáš Kostlivý
Journal:  Ann Thorac Cardiovasc Surg       Date:  2022-03-08       Impact factor: 1.889

Review 3.  Complications of peritonsillar abscess.

Authors:  Tejs Ehlers Klug; Thomas Greve; Malene Hentze
Journal:  Ann Clin Microbiol Antimicrob       Date:  2020-07-30       Impact factor: 3.944

  3 in total

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