Literature DB >> 3199669

Localization of the gene for X-linked Alport's syndrome.

H Brunner1, C Schröder, C van Bennekom, E Lambermon, J Tuerlings, D Menzel, H Olbing, L Monnens, B Wieringa, H H Ropers.   

Abstract

X-chromosomal DNA probes defining various polymorphic DNA markers were used to study genetic linkage in three families with Alport's syndrome. With the DXS17 marker, only a single cross-over was observed in 26 informative meioses, and evidence for linkage was also obtained with the DXS11 marker. These data localize the gene for the X-linked form of Alport's syndrome to the middle of the long arm of the X chromosome.

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Year:  1988        PMID： 3199669     DOI： 10.1038/ki.1988.210

Source DB:  PubMed          Journal:  Kidney Int        ISSN： 0085-2538            Impact factor:   10.612


  17 in total

1.  The molecular genetics of Alport syndrome: report of two workshops.

Authors:  F Flinter; M Bobrow
Journal:  J Med Genet       Date:  1992-05       Impact factor: 6.318

2.  Alport syndrome: a genetic study of 31 families.

Authors:  R M'Rad; M Sanak; G Deschenes; J Zhou; C Bonaiti-Pellie; L Holvoet-Vermaut; S Heuertz; M C Gubler; M Broyer; J P Grunfeld
Journal:  Hum Genet       Date:  1992-12       Impact factor: 4.132

Review 3.  Alport syndrome, basement membranes and collagen.

Authors:  C E Kashtan; M M Kleppel; R J Butkowski; A F Michael; A J Fish
Journal:  Pediatr Nephrol       Date:  1990-09       Impact factor: 3.714

4.  The gene corresponding to the putative Goodpasture antigen is present in Alport's syndrome.

Authors:  J A Savige
Journal:  Clin Exp Immunol       Date:  1991-08       Impact factor: 4.330

5.  Should women who are known or potential carriers of the Alport gene be accepted as kidney donors?

Authors:  C E Kashtan
Journal:  Pediatr Nephrol       Date:  1990-05       Impact factor: 3.714

6.  Mutation in the alpha 5(IV) collagen chain in juvenile-onset Alport syndrome without hearing loss or ocular lesions: detection by denaturing gradient gel electrophoresis of a PCR product.

Authors:  J Zhou; J M Hertz; K Tryggvason
Journal:  Am J Hum Genet       Date:  1992-06       Impact factor: 11.025

Review 7.  Alport's syndrome.

Authors:  F Flinter
Journal:  J Med Genet       Date:  1997-04       Impact factor: 6.318

8.  Canine X chromosome-linked hereditary nephritis: a genetic model for human X-linked hereditary nephritis resulting from a single base mutation in the gene encoding the alpha 5 chain of collagen type IV.

Authors:  K Zheng; P S Thorner; P Marrano; R Baumal; R R McInnes
Journal:  Proc Natl Acad Sci U S A       Date:  1994-04-26       Impact factor: 11.205

9.  Sequence and localization of a partial cDNA encoding the human alpha 3 chain of type IV collagen.

Authors:  K E Morrison; M Mariyama; T L Yang-Feng; S T Reeders
Journal:  Am J Hum Genet       Date:  1991-09       Impact factor: 11.025

10.  X inactivation patterns in females with Alport's syndrome: a means of selecting against a deleterious gene?

Authors:  D Vetrie; F Flinter; M Bobrow; A Harris
Journal:  J Med Genet       Date:  1992-09       Impact factor: 6.318
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