Literature DB >> 31996384

Rapidly progressing HELLP syndrome and massive liver destruction in a 22-year-old female pregnant with monochorionic diamniotic gemelli.

Julie Brøsen1, Dorte Stærk2, Anne-Dorthe Feldthusen3, Allan Rasmussen4, Mette Brimnes Damholt5.   

Abstract

Haemolysis Elevated Liver parameters and Low Platelets (HELLP) syndrome can present with abdominal pain as the only symptom. It can be rapid with failure of multiple organs and is a cause of maternal death. A 22-year-old female pregnant with twins contacted her local hospital due to abdominal pain. Within 20 hours of the debut of the abdominal pain, a caesarean section was performed, the patient was re-operated due to the suspicion of abdominal bleeding. Bescause she was hypotensive and blood tests showed signs of liver destruction and acidosis, she was transferred to the intensive care unit (ICU). During an admission of 40 days, the patient received 5 plasmapheresis treatments and 10 courses of haemodialysis. CT scans showed massive liver haematomas intraparenchymal and subcapsular. The CT scan images are very interesting and included in the case report.This case presents a good prognosis after a rapid progression of HELLP in spite of a dramatic clinical presentation. This topic is of great interest to a wide spectre of clinicians, as an early multidisciplinary approach is necessary. © BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  acute renal failure; adult intensive care; dialysis; pregnancy

Mesh:

Year:  2020        PMID: 31996384      PMCID: PMC7021145          DOI: 10.1136/bcr-2019-229458

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  13 in total

Review 1.  An Unusual Medicolegal Case of 32-Year-Old Mother and Her 29-Week Fetus With Hemolysis, Elevated Liver Enzymes, and Low Platelet Count Syndrome: Case Report and Short Literature Review.

Authors:  Michał Szeremeta; Petra Drobuliakova; Jerzy Przepieść; Janusz Załuski; Adam Sackiewicz; Anna Niemcunowicz-Janica
Journal:  Am J Forensic Med Pathol       Date:  2017-09       Impact factor: 0.921

2.  Peripartum Patient With Epigastric Pain.

Authors:  Davinia Ryan; Giuseppe Cruciata; Serena Monti; Pier Luigi Di Paolo; Lorenzo Mannelli
Journal:  Ann Emerg Med       Date:  2017-09       Impact factor: 5.721

Review 3.  Diagnosis and Management of HELLP Syndrome Complicated by Liver Hematoma.

Authors:  Agnès Ditisheim; Baha M Sibai
Journal:  Clin Obstet Gynecol       Date:  2017-03       Impact factor: 2.190

Review 4.  Liver diseases unique to pregnancy: a 2010 update.

Authors:  Yannick Bacq
Journal:  Clin Res Hepatol Gastroenterol       Date:  2011-03       Impact factor: 2.947

Review 5.  Diagnosis, controversies, and management of the syndrome of hemolysis, elevated liver enzymes, and low platelet count.

Authors:  Baha M Sibai
Journal:  Obstet Gynecol       Date:  2004-05       Impact factor: 7.661

Review 6.  Why kidneys fail post-partum: a tubulocentric viewpoint.

Authors:  Patricia Villie; Marc Dommergues; Isabelle Brocheriou; Giorgina Barbara Piccoli; Jérôme Tourret; Alexandre Hertig
Journal:  J Nephrol       Date:  2018-04-10       Impact factor: 3.902

Review 7.  Preeclampsia, a disease of the maternal endothelium: the role of antiangiogenic factors and implications for later cardiovascular disease.

Authors:  Camille E Powe; Richard J Levine; S Ananth Karumanchi
Journal:  Circulation       Date:  2011-06-21       Impact factor: 29.690

Review 8.  Hepatic infarction induced by HELLP syndrome: a case report and review of the literature.

Authors:  Qinyue Guo; Zhengfei Yang; Jian Guo; Lei Zhang; Lan Gao; Bo Zhou; Qindong Shi
Journal:  BMC Pregnancy Childbirth       Date:  2018-05-30       Impact factor: 3.007

Review 9.  Global causes of maternal death: a WHO systematic analysis.

Authors:  Lale Say; Doris Chou; Alison Gemmill; Özge Tunçalp; Ann-Beth Moller; Jane Daniels; A Metin Gülmezoglu; Marleen Temmerman; Leontine Alkema
Journal:  Lancet Glob Health       Date:  2014-05-05       Impact factor: 26.763

10.  HELLP Syndrome Complicated by Subcapsular Hematoma of Liver: A Case Report and Review of the Literature.

Authors:  Atilla Karateke; Dilek Silfeler; Faruk Karateke; Raziye Kurt; Ayse Guler; Ismail Kartal
Journal:  Case Rep Obstet Gynecol       Date:  2014-04-02
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