Literature DB >> 31995337

The economic impact of periprosthetic infection in total hip arthroplasty

Jason Akindolire1, Mina W. Morcos1, Jacquelyn D. Marsh1, James L. Howard1, Brent A. Lanting1, Edward M. Vasarhelyi1.   

Abstract

Background: Periprosthetic joint infection (PJI) is the third leading cause of total hip arthroplasty (THA) failure. Although controversial, 2-stage revision remains the gold standard treatment for PJI in most situations. To date, there have been few studies describing the economic impact of PJI in today’s health care environment. The purpose of the current study was to obtain an accurate estimate of the institutional cost associated with the management of PJI in THA and to assess the economic burden of PJI compared with primary uncomplicated THA.
Methods: We conducted a review of primary THA cases and 2-stage revision THA for PJI at our institution. Patients were matched for age and body mass index. All costs associated with each procedure were recorded. Descriptive statistics were used to summarize the collected data. Mean costs, length of stay, clinic visits and readmission rates associated with the 2 cohorts were compared.
Results: Fifty consecutive cases of revision THA were matched with 50 cases of uncomplicated primary THA between 2006 and 2014. Compared with the primary THA cohort, PJI was associated with a significant increase in mean length of hospital stay (26.5 v. 2.0 d, p < 0.001), mean number of clinic visits (9.2 v. 3.8, p < 0.001), number of readmissions (12 v. 1, p < 0.001) and average overall cost (Can$38 107 v. Can$6764, t = 8.3, p < 0.001).
Conclusion: Treatment of PJI is a tremendous economic burden. Our data suggest a 5-fold increase in hospital expenditure in the management of PJI compared with primary uncomplicated THA.
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Year:  2020        PMID: 31995337      PMCID: PMC7828941          DOI: 10.1503/cjs.004219

Source DB:  PubMed          Journal:  Can J Surg        ISSN: 0008-428X            Impact factor:   2.089


  16 in total

1.  Quantifying the Burden of Revision Total Joint Arthroplasty for Periprosthetic Infection.

Authors:  Atul F Kamath; Kevin L Ong; Edmund Lau; Vanessa Chan; Thomas P Vail; Harry E Rubash; Daniel J Berry; Kevin J Bozic
Journal:  J Arthroplasty       Date:  2015-03-31       Impact factor: 4.757

2.  The impact of infection after total hip arthroplasty on hospital and surgeon resource utilization.

Authors:  Kevin J Bozic; Michael D Ries
Journal:  J Bone Joint Surg Am       Date:  2005-08       Impact factor: 5.284

3.  One-stage exchange arthroplasty for chronic periprosthetic hip infection: results of a large prospective cohort study.

Authors:  Valérie Zeller; Luc Lhotellier; Simon Marmor; Philippe Leclerc; Alysa Krain; Wilfrid Graff; Françoise Ducroquet; David Biau; Philippe Leonard; Nicole Desplaces; Patrick Mamoudy
Journal:  J Bone Joint Surg Am       Date:  2014-01-01       Impact factor: 5.284

4.  Age and obesity are risk factors for adverse events after total hip arthroplasty.

Authors:  James I Huddleston; Yun Wang; Carlos Uquillas; James H Herndon; William J Maloney
Journal:  Clin Orthop Relat Res       Date:  2012-02       Impact factor: 4.176

5.  Periprosthetic Infection following Primary Hip and Knee Arthroplasty: The Impact of Limiting the Postoperative Surveillance Period.

Authors:  Virginia R Roth; Robyn Mitchell; Julie Vachon; Stéphanie Alexandre; Kanchana Amaratunga; Stephanie Smith; Mary Vearncombe; Ian Davis; Dominik Mertz; Elizabeth Henderson; Michael John; Lynn Johnston; Camille Lemieux; Linda Pelude; Denise Gravel
Journal:  Infect Control Hosp Epidemiol       Date:  2016-11-11       Impact factor: 3.254

6.  The economic significance of orthopaedic infections.

Authors:  Daniel J Hackett; Adam C Rothenberg; Antonia F Chen; Christina Gutowski; David Jaekel; Ivan M Tomek; Brian S Parsley; Paul Ducheyne; Paul A Manner
Journal:  J Am Acad Orthop Surg       Date:  2015-04       Impact factor: 3.020

7.  Comparative Epidemiology of Revision Arthroplasty: Failed THA Poses Greater Clinical and Economic Burdens Than Failed TKA.

Authors:  Kevin J Bozic; Atul F Kamath; Kevin Ong; Edmund Lau; Steve Kurtz; Vanessa Chan; Thomas P Vail; Harry Rubash; Daniel J Berry
Journal:  Clin Orthop Relat Res       Date:  2014-12-03       Impact factor: 4.176

8.  Hospital resource utilization for primary and revision total hip arthroplasty.

Authors:  Kevin J Bozic; Patricia Katz; Miriam Cisternas; Linda Ono; Michael D Ries; Jonathan Showstack
Journal:  J Bone Joint Surg Am       Date:  2005-03       Impact factor: 5.284

9.  The Economic Impact of Periprosthetic Infections After Total Hip Arthroplasty at a Specialized Tertiary-Care Center.

Authors:  Bhaveen H Kapadia; Samik Banerjee; Jeffrey J Cherian; Kevin J Bozic; Michael A Mont
Journal:  J Arthroplasty       Date:  2016-01-21       Impact factor: 4.757

Review 10.  What is the evidence base to guide surgical treatment of infected hip prostheses? systematic review of longitudinal studies in unselected patients.

Authors:  Andrew D Beswick; Karen T Elvers; Alison J Smith; Rachael Gooberman-Hill; Andrew Lovering; Ashley W Blom
Journal:  BMC Med       Date:  2012-02-16       Impact factor: 8.775

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  8 in total

1.  What is the rate of reinfection with different and difficult-to-treat bacteria after failed one-stage septic knee exchange?

Authors:  Mustafa Akkaya; Georges Vles; Iman Godarzi Bakhtiari; Amir Sandiford; Jochen Salber; Thorsten Gehrke; Mustafa Citak
Journal:  Int Orthop       Date:  2022-01-04       Impact factor: 3.075

2.  Periprosthetic Knee Infection - Part 1: Risk Factors, Classification and Diagnosis.

Authors:  João Maurício Barretto; André Luiz Siqueira Campos; Nelson Hiroyuki Miyabe Ooka
Journal:  Rev Bras Ortop (Sao Paulo)       Date:  2022-05-27

3.  Current and Future Burden of Periprosthetic Joint Infection from National Claim Database.

Authors:  Hong Seok Kim; Jung Wee Park; Sun Young Moon; Young Kyun Lee; Yong Chan Ha; Kyung Hoi Koo
Journal:  J Korean Med Sci       Date:  2020-12-21       Impact factor: 2.153

4.  The economic impact of periprosthetic infection in total knee arthroplasty.

Authors:  Mina W Morcos; Paul Kooner; Jackie Marsh; James Howard; Brent Lanting; Edward Vasarhelyi
Journal:  Can J Surg       Date:  2021-03-05       Impact factor: 2.089

Review 5.  Application of leukocyte esterase strip test in the screening of periprosthetic joint infections and prospects of high-precision strips.

Authors:  Qing-Yuan Zheng; Guo-Qiang Zhang
Journal:  Arthroplasty       Date:  2020-10-29

6.  A 92 protein inflammation panel performed on sonicate fluid differentiates periprosthetic joint infection from non-infectious causes of arthroplasty failure.

Authors:  Cody R Fisher; Harold I Salmons; Jay Mandrekar; Kerryl E Greenwood-Quaintance; Matthew P Abdel; Robin Patel
Journal:  Sci Rep       Date:  2022-09-27       Impact factor: 4.996

7.  Vastus lateralis versus rectus femoris muscle flaps for recalcitrant hip joint infection: An anatomical study comparing the effectiveness of acetabular dead space control.

Authors:  Alexandria H Smith; Cecilia Brassett; Christopher Gooding; Ahid Abood; Alan Norrish
Journal:  Clin Anat       Date:  2022-07-02       Impact factor: 2.409

8.  What Are the Long-term Outcomes of Mortality, Quality of Life, and Hip Function after Prosthetic Joint Infection of the Hip? A 10-year Follow-up from Sweden.

Authors:  Peter Wildeman; Ola Rolfson; Bo Söderquist; Per Wretenberg; Viktor Lindgren
Journal:  Clin Orthop Relat Res       Date:  2021-10-01       Impact factor: 4.755

  8 in total

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