Literature DB >> 31994894

Genome Mining and Biosynthesis of Primary Amine-Acylated Desferrioxamines in a Marine Gliding Bacterium.

Zong-Jie Wang1, Haibo Zhou1, Guannan Zhong1, Liujie Huo1, Ya-Jie Tang1, Youming Zhang1, Xiaoying Bian1.   

Abstract

Genome mining of Fulvivirga sp. W222 revealed a desferrioxamine-like biosynthetic gene cluster containing an unknown gene fulF that is conserved in many Bacteroidetes species. A series of primary amine-acylated desferrioxamine G1 analogues, fulvivirgamides, were identified, and fulvivirgamides A2, B2, B3, and B4 (1-4) were purified and characterized. The function of FulF, which is a novel acyltransferase for the acylation of the primary amine of Desferrioxamine G1, was verified by heterologous expression and feeding experiments.

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Year:  2020        PMID： 31994894     DOI： 10.1021/acs.orglett.9b04490

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  5 in total

1.  Microbiome composition modulates secondary metabolism in a multispecies bacterial community.

Authors:  Marc G Chevrette; Chris S Thomas; Amanda Hurley; Natalia Rosario-Meléndez; Kris Sankaran; Yixing Tu; Austin Hall; Shruthi Magesh; Jo Handelsman
Journal:  Proc Natl Acad Sci U S A       Date:  2022-10-10       Impact factor: 12.779

Review 2.  Biosynthesis of C-nucleoside antibiotics in actinobacteria: recent advances and future developments.

Authors:  Meng Zhang; Liyuan Kong; Rong Gong; Marianna Iorio; Stefano Donadio; Zixin Deng; Margherita Sosio; Wenqing Chen
Journal:  Microb Cell Fact       Date:  2022-01-04       Impact factor: 5.328

3.  Engineering and elucidation of the lipoinitiation process in nonribosomal peptide biosynthesis.

Authors:  Lin Zhong; Xiaotong Diao; Na Zhang; Fengwei Li; Haibo Zhou; Hanna Chen; Xianping Bai; Xintong Ren; Youming Zhang; Dalei Wu; Xiaoying Bian
Journal:  Nat Commun       Date:  2021-01-12       Impact factor: 14.919

4.  Genome Mining, Heterologous Expression, Antibacterial and Antioxidant Activities of Lipoamides and Amicoumacins from Compost-Associated Bacillus subtilis fmb60.

Authors:  Jie Yang; Qingzheng Zhu; Feng Xu; Ming Yang; Hechao Du; Xiaoying Bian; Zhaoxin Lu; Yingjian Lu; Fengxia Lu
Journal:  Molecules       Date:  2021-03-26       Impact factor: 4.411

5.  A Metataxonomic Approach Reveals Diversified Bacterial Communities in Antarctic Sponges.

Authors:  Nadia Ruocco; Roberta Esposito; Marco Bertolino; Gianluca Zazo; Michele Sonnessa; Federico Andreani; Daniela Coppola; Daniela Giordano; Genoveffa Nuzzo; Chiara Lauritano; Angelo Fontana; Adrianna Ianora; Cinzia Verde; Maria Costantini
Journal:  Mar Drugs       Date:  2021-03-22       Impact factor: 5.118
  5 in total

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