Yite Xu1,2, Jie Qin1, Pan Wang1, Qiuxia Li1, Shasha Yu1, Yanling Zhang3, Ying Wang1. 1. Department of Tropical Medicine, College of Preventive Medicine, Army Medical University, Chongqing 400038, China. 2. The 10th Squadron, The 3rd Brigade, College of Basic Medicine, Army Medical University, Chongqing 400038, China. 3. Department of Neurology, Southwest Hospital, Army Medical University, Chongqing 400038, China.
Abstract
INTRODUCTION: Anopheles stephensi is the main malaria vector in Southeast Asia. Recently, plant-sourced larvicides are attracting great interests. METHODS: The essential oil was extracted from the leaf of Cinnamomum camphora (L.), and a bioassay was conducted to determine the larvicidal efficacy. The chemical composition of the essential oil was determined by GC-MS analysis. RESULTS: The oil showed strong, dose-dependent larvicidal activities. The onset of larvicidal efficiency was rapid. The LC50 and LC95 were determined as 0.146% and 1.057% at 1 h, 0.031% and 0.237% at 12 h, 0.026% and 0.128% at 24 h, respectively. The oil contains 32 compounds. CONCLUSIONS: The essential oil of C. camphora leaf has an excellent larvicidal potential for the control of A. stephensi.
INTRODUCTION:Anopheles stephensi is the main malaria vector in Southeast Asia. Recently, plant-sourced larvicides are attracting great interests. METHODS: The essential oil was extracted from the leaf of Cinnamomum camphora (L.), and a bioassay was conducted to determine the larvicidal efficacy. The chemical composition of the essential oil was determined by GC-MS analysis. RESULTS: The oil showed strong, dose-dependent larvicidal activities. The onset of larvicidal efficiency was rapid. The LC50 and LC95 were determined as 0.146% and 1.057% at 1 h, 0.031% and 0.237% at 12 h, 0.026% and 0.128% at 24 h, respectively. The oil contains 32 compounds. CONCLUSIONS: The essential oil of C. camphora leaf has an excellent larvicidal potential for the control of A. stephensi.